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  • ICU Fellowship (CICM)
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© 2026 MedVellum. For education only — not a substitute for clinical judgement.

Folio edition · Set in Instrument Serif & Archivo

Primary & Final

Anaesthesia

Airway, pharmacology, and peri-operative physiology — structured for ANZCA primary and final.

Start with topicsBrowse SAQs
Anaesthesia theatre atmosphere
Plate — primary & finalMedVellum Press
265Topics
3SAQs
1Cases
2Vivas

Study by format

Four ways through Anaes — one evidence base.

265

Topics

Browse topics for Anaes.

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3

SAQs

Browse saqs for Anaes.

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Cases

Browse cases for Anaes.

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2

Vivas

Browse vivas for Anaes.

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Live topics

Open a figure-rich spine

All topics
★ High yield
Vascular anaesthesia

AAA open repair versus EVAR: anaesthetic decision matrix

Exam-exhaustive open AAA vs EVAR anaesthesia for ANZCA Final.

ANZCAFRCA
★ High yield
Applied anatomy

Abdominal wall and fascial planes

The abdominal wall is the setting for a generation of fascial-plane regional blocks (the TAP, rectus sheath, quadratus lumborum and erector spinae plane blocks) that have transformed analgesia for abdominal surgery, and for the laparoscopic port sites and surgical incisions of the abdomen. The framework rests on six exam-critical ideas. First, the anterolateral abdominal wall is built of nine layers from superficial to deep: skin, subcutaneous fat (Camper's fascia), the membranous layer (Scarpa's fascia), the three flat muscles (external oblique, internal oblique, transversus abdominis) with their aponeuroses, the transversalis fascia, the extraperitoneal fat, and the parietal peritoneum. Second, the midline is closed by the LINEA ALBA, the fusion of the three aponeuroses, into which the rectus abdominis muscles sit either side wrapped in the RECTUS SHEATH; the sheath's composition changes at the ARCUATE LINE (about halfway between the umbilicus and the pubis), below which the posterior wall is transversalis fascia only. Third, the wall is innervated segmentally by the thoracoabdominal nerves (the anterior rami of T7 to T11), the SUBCOSTAL nerve (T12) and the ILIOHYPOGASTRIC and ILIOINGUINAL nerves (L1); the motor and sensory branches of T7-L1 run in the fascial plane between the internal oblique and transversus abdominis — the TRANSVERSUS ABDOMINIS PLANE (TAP). Fourth, the TAP block deposits local anaesthetic in this plane to anaesthetise the anterior abdominal wall (the anterolateral skin and the parietal peritoneum), giving analgesia for lower-abdominal surgery such as caesarean section, hysterectomy and hernia repair. Fifth, the related fascial-plane blocks target planes at different depths and spread — the RECTUS SHEATH block (between rectus and posterior sheath, for midline incisions), the QUADRATUS LUMBORUM block (the pararenal plane, which can spread to the thoracic paravertebral space and cover the visceral as well as the somatic abdominal wall), and the ERECTOR SPINAE PLANE block (the plane over the erector spinae, with cranial-caudal spread for thoracic and abdominal wall analgesia). Sixth, the inguinal canal and the surface landmarks (umbilicus at L4/L5, McBurney's point at the appendix, the semilunar line of the rectus border) complete the applied anatomy for hernia surgery and port placement. Built on the TAP-versus-ilioinguinal-iliohypogastric study (Reda 2026), the hyaluronidase-TAP study (Amin 2026), the erector-spinae-versus-paravertebral study (Turhan 2026), the classical-versus-deep rectus-sheath study (Chooklin 2026), the combined quadratus-lumborum study (Ji 2026), the inguinal-hernia-repair study (Filip 2026), the inguinal-canal spermatic-cord study (Tepelenis 2026), and the umbilical endometriosis study (Huang 2026).

ANZCAFRCA
★ High yield
Depth of anaesthesia & awareness

Accidental awareness under general anaesthesia: NAP5 and prevention

Exam-pass AAGA topic built on NAP5: incidence, risk groups (TIVA, NMB, obstetrics, cardiac, emergency), end-tidal agent alarms, processed-EEG when agent unmeasured, Brice interview, compassionate response, and B-Aware/BAG-RECALL context for ANZCA Final and FRCA.

ANZCAFRCA
★ High yield
Applied cardiovascular & respiratory physiology

Acid-base: buffers & compensation

Arterial pH is held between 7.35 and 7.45 by a system of buffers and two excretory organs, and the anaesthetist reads its output every time a blood gas is drawn. Six exam-critical ideas frame the topic. First, pH is governed by the Henderson-Hasselbalch relationship, in which pH equals pKa plus the log of the ratio of bicarbonate to dissolved carbon dioxide (0.03 times PaCO2), so the bicarbonate to PaCO2 ratio sets the pH. Second, the bicarbonate buffer dominates the extracellular fluid not because its pKa (6.1) is well matched to pH 7.4 but because it is an OPEN system, the lungs exhaling the acid (CO2) and the kidneys regenerating the base (bicarbonate). Third, the non-bicarbonate buffers, chiefly haemoglobin (imidazole of histidine, pKa about 7.0, with deoxyhaemoglobin the better buffer, the Haldane effect), plasma proteins and phosphate, supply the buffer base. Fourth, there are four primary disorders, respiratory acidosis and alkalosis (a PaCO2 problem) and metabolic acidosis and alkalosis (a bicarbonate problem), each compensated by the opposite system, respiratory compensation fast (minutes to hours) and renal compensation slow (two to five days). Fifth, the expected compensations are rule-based and must be checked, the chief being Winter's formula (expected PaCO2 equals 1.5 times bicarbonate plus 8, plus or minus 2 for metabolic acidosis) and the acute versus chronic respiratory rules (acute respiratory acidosis adds about 1 mmol per litre of bicarbonate per 10 mmHg rise in PaCO2, chronic adds about 4; acute respiratory alkalosis drops about 2 per 10, chronic about 4 to 5). Sixth, base excess (the metabolic component at a standardised PaCO2 of 40 mmHg) and the anion gap (sodium minus chloride minus bicarbonate) are the two derived variables that refine the diagnosis. Built on the Adrogue and Madias acid-base reviews (NEJM 1998), the Berend base-excess review (NEJM 2018), the Story acid-base history (Critical Care 2004), the Kellum determinants review (Critical Care Clinics 2005), the Figge serum-protein buffer study (1991), the Madias renal acidification reviews (Nephron Physiology 2003, Journal of Nephrology 2010), the Fulop PaCO2-prediction study (1997), the Kraut and Madias lactic-acidosis review (2016), the Lang and Zander base-excess calculation study (2002), and the Berend acid-base pathophysiology review (2013).

ANZCAFRCA
★ High yield
Applied cardiovascular & respiratory physiology

Acid-base: the Stewart approach

Peter Stewart's physicochemical approach reinterprets acid-base in terms of three independent variables that determine the dependent variable, pH, by mass-action: the carbon dioxide tension, the strong ion difference (the net charge of fully dissociated ions, dominated by sodium and chloride), and the total concentration of weak acid (chiefly albumin and phosphate). The framework rests on five exam-critical ideas: only three independent variables set the pH — PaCO2, the strong ion difference, and total weak acid; the strong ion difference (normally about 38 to 42 mmol per litre, dominated by sodium minus chloride) is the principal metabolic lever, and a fall in the SID (a chloride rise) causes metabolic acidosis while a rise causes alkalosis; total weak acid is mainly albumin, so hypoalbuminaemia causes a metabolic alkalosis that can mask a coexisting acidosis; bicarbonate is a DEPENDENT variable in Stewart's view (it changes to maintain electroneutrality), not a cause; and the Stewart approach explains the hyperchloraemic metabolic acidosis of large-volume normal saline, the hypoalbuminaemic alkalosis of critical illness, and unmeasured anions (the strong ion gap) that the bicarbonate method can miss. Built on the Stewart acid-base recovery study (Samara 2026), the dialysis acid-base comparative analysis (Kroustalakis 2025), the physicochemical COVID acid-base study (de Souza 2024), the balanced-crystalloids versus saline studies (Carrigan 2026, Sweety 2026), and the robotic-surgery (CO2 pneumoperitoneum) acid-base study (Pitimada 2026).

ANZCAFRCA
Acute pain & multimodal analgesia

Acute pain & multimodal analgesia

Exam-exhaustive acute pain: WHO-style ladder adapted to acute surgical pain, multimodal components with doses, PCA principles, regional integration, and brief opioid-tolerant patient strategy.

ANZCAFRCA

How this hub is built

Exam-exhaustive. Source-backed. Format-complete.

Topics carry the clinical spine. SAQs, cases, and vivas force the same knowledge into the formats you will sit. Claims are written for examiners — and cited for trust.

Cited claims

PubMed-linked references on clinical statements.

Labelled figures

Algorithms and frameworks built for recall.

Format rails

MCQ, SAQ/MEQ, case, and viva for the same spine.

Board tags

FRANZCP, ACEM, CICM, ANZCA and global peers.