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Anaes TopicsAcute pain & multimodal analgesia

Anaes · Acute pain & multimodal analgesia

Acute pain & multimodal analgesia

Also known as Acute pain service · Multimodal analgesia · Opioid-sparing · PCA · Fascial plane blocks · Postoperative pain

Exam-exhaustive acute pain: WHO-style ladder adapted to acute surgical pain, multimodal components with doses, PCA principles, regional integration, and brief opioid-tolerant patient strategy.

medium3 referencesUpdated 26 July 20267 min readVerification in progress

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ANZCAFRCAABAEDAICFCAI

Red flags

  • Uncontrolled acute pain causes atelectasis, ileus, DVT risk, delayed mobilisation, and chronic postsurgical pain — treat function, not only the number.
  • PCA background infusions in opioid-naïve patients increase respiratory depression risk — usually avoid.
  • Opioid-tolerant patients need baseline continuation + multimodal + regional/ketamine — not moralising dose cuts.
  • Epidural haematoma/abscess and LAST are regional emergencies — know the pathways.
  • Multimodal means different mechanisms — not three opioids.
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

ANZCAFRCAABAEDAICFCAI

Red flags

  • Uncontrolled acute pain causes atelectasis, ileus, DVT risk, delayed mobilisation, and chronic postsurgical pain — treat function, not only the number.
  • PCA background infusions in opioid-naïve patients increase respiratory depression risk — usually avoid.
  • Opioid-tolerant patients need baseline continuation + multimodal + regional/ketamine — not moralising dose cuts.
  • Epidural haematoma/abscess and LAST are regional emergencies — know the pathways.
  • Multimodal means different mechanisms — not three opioids.
The one-line answer

Build acute analgesia from non-opioid foundations upward. Regular paracetamol and NSAID or COX-2 if safe, add regional or local wherever it changes outcomes, use the lowest effective opioid via oral or PCA routes, monitor sedation and ventilation, and escalate through the acute pain service when the trajectory is wrong (taught multimodal framework — the LAST advisory [1] owns no ladder claim).[1]

Meet the patient

A 68-year-old man is day one after open colectomy. His pain is 8 out of 10 on movement, he cannot cough or mobilise, and the ward nurse has been pressing his PCA button for him — proxy pressing that breaks the core PCA safety rule (taught safety rule — the LAST advisory [1] owns no PCA claim). The question the acute pain service asks on review is the one that changes the trajectory: is this an opioid-dose problem, or a multimodal-gap problem?[1]

The answer is almost always the latter. The PCA bolus was increased twice overnight with no improvement, because the foundation — regular paracetamol, NSAID, regional technique — was never laid. Multimodal means different mechanisms, not three opioids (taught framework).[1]

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References3ShowHide
  1. [1]Neal JM et al. The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity: Executive Summary 2017 Reg Anesth Pain Med, 2018.PMID 29356773
  2. [2]Horlocker TT et al. Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition) Reg Anesth Pain Med, 2018.PMID 29561531
  3. [3]Gan TJ, et al. Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting Anesth Analg, 2020.PMID 32467512

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