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EM TopicsToxicology and environmental emergencies

EM · Toxicology and environmental emergencies

Bites and stings

Also known as Mammalian bite · Dog bite · Cat bite · Human bite · Clenched-fist injury · Insect sting · Bee sting · Wasp sting · Stingray injury · Marine puncture wound · Snake bite · Elapid envenomation · Pressure immobilisation bandage · Redback spider bite · Funnel-web spider bite · Latrodectism · Box jellyfish sting · Blue-ringed octopus bite · Stonefish sting · Venom-induced consumption coagulopathy

Bites and stings in the Australasian ED — polymicrobial mammalian bites (median 4 isolates in human bites), bee/wasp stings with anaphylaxis risk, stingray punctures relieved by hot-water immersion, Australian snakebite with VICC, widow/funnel-web spiders, and box jellyfish. Amoxicillin-clavulanate shows excellent in vitro activity; prophylaxis benefits human and hand bites; IM adrenaline is first-line for anaphylaxis; antivenoms exist only for sea snakes, Chironex, and stonefish.

low26 referencesUpdated 26 July 202618 min readSource-verified · Oct 2026

Checked against its sources on 14 Oct 2026

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ACEMFRCEMABEMFRCPCCCFPEMEBEEM

Red flags

  • Cat bites, puncture wounds, and hand wounds carry high infection risk — consider prophylaxis; amoxicillin-clavulanate showed excellent in vitro activity against common bite isolates.
  • The clenched-fist injury seeds joint, sheath, and bone — explore every wound for tendon, bone, and foreign bodies; refer joint involvement to hand surgery for washout and IV antibiotics.
  • Stingray pain: hot-water immersion gives 88% complete relief within 30 min alone — then explore for retained stinger, sheath, or barb, which radiography misses.
  • An insect sting can cause anaphylaxis — IM adrenaline is first-line; biphasic reactions occur mostly within 72 h, so observe after resolution.
  • Rabies is universally fatal once symptomatic — consider post-exposure prophylaxis for any bat bite (anywhere, including ANZ) and for any dog or monkey bite sustained overseas; irrigate, and seek public-health advice on vaccine and immunoglobulin.
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Related topics

  • Snake envenomation
  • Spider and marine envenomation
  • Wound assessment and management
  • Wound closure and suturing techniques
  • The toxidrome approach and the general management of the poisoned patient
  • Sepsis and septic shock — the emergency department approach
Study tools

Your progress

Saved on this device.

Practise this topic6 MCQs with explanations

Target exams

ACEMFRCEMABEMFRCPCCCFPEMEBEEM

Red flags

  • Cat bites, puncture wounds, and hand wounds carry high infection risk — consider prophylaxis; amoxicillin-clavulanate showed excellent in vitro activity against common bite isolates.
  • The clenched-fist injury seeds joint, sheath, and bone — explore every wound for tendon, bone, and foreign bodies; refer joint involvement to hand surgery for washout and IV antibiotics.
  • Stingray pain: hot-water immersion gives 88% complete relief within 30 min alone — then explore for retained stinger, sheath, or barb, which radiography misses.
  • An insect sting can cause anaphylaxis — IM adrenaline is first-line; biphasic reactions occur mostly within 72 h, so observe after resolution.
  • Rabies is universally fatal once symptomatic — consider post-exposure prophylaxis for any bat bite (anywhere, including ANZ) and for any dog or monkey bite sustained overseas; irrigate, and seek public-health advice on vaccine and immunoglobulin.
The one-line answer

Bites and stings turn on polymicrobial wounds, venom syndromes, and first-aid specifics. Mammalian bites are polymicrobial (median 4 isolates in human bites) — amoxicillin-clavulanate showed excellent in vitro activity; prophylaxis benefits human and hand bites. Stingray pain responds to hot-water immersion (88% relief within 30 min). An insect sting can cause anaphylaxis — intramuscular adrenaline is first-line; biphasic reactions occur mostly within 72 h.[2][4][15][22]

Meet the patient

A 22-year-old man punches someone, opens his hand, and notices a tiny laceration over the knuckle. Hours later the metacarpophalangeal joint is hot, swollen and agonising. It is a clenched-fist injury — the tooth seeds Eikenella (30% of human-bite isolates) plus aerobes and anaerobes into joint and sheath — referred to hand surgery for washout and IV antibiotics, with the wound explored for tendon, bone, and foreign bodies.[1][2]

Hold three patterns at once — mammalian oral flora, heat-labile marine venom, and Hymenoptera hypersensitivity — and the antibiotic, the first aid and the antidote for each bite and sting fall into place.[3]

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References26ShowHide
  1. [1]Ellis R, Ellis C. Dog and cat bites. American Family Physician, 2014.PMID 25250997
  2. [2]Talan DA, Abrahamian FM, Moran GJ, Citron DM, Tan JO, Goldstein EJ. Clinical presentation and bacteriologic analysis of infected human bites in patients presenting to emergency departments. Clinical Infectious Diseases, 2003.PMID 14614671
  3. [3]Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. Journal of the American Academy of Dermatology, 1995.PMID 7490347
  4. [4]Clark RF, Girard RH, Rao D, Ly BT, Davis DP. Stingray envenomation: a retrospective review of clinical presentation and treatment in 119 cases. The Journal of Emergency Medicine, 2007.PMID 17630073
  5. [5]Niżnik Ł, Jabłońska K, Orczyk M, et al. Hot-water immersion (HWI) or ice-pack treatment (IPT) as first aid for human envenomations — a scoping review. Toxins, 2024.PMID 38922167
  6. [6]Manning SE, Rupprecht CE, Fishbein DB, et al. Human rabies prevention — United States, 2008: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recommendations and Reports, 2008.PMID 18496505
  7. [7]Warrell DA. Snake bite. Lancet, 2010.PMID 20109866
  8. [8]Isbister GK, Fan HW. Spider bite. Lancet, 2011.PMID 21762981
  9. [9]Currie BJ, Jacups SP. Prospective study of Chironex fleckeri and other box jellyfish stings in the 'Top End' of Australia's Northern Territory. Medical Journal of Australia, 2005.PMID 16336157
  10. [10]Currie BJ. Treatment of snakebite in Australia: the current evidence base and questions requiring collaborative multicentre prospective studies. Toxicon, 2006.PMID 16930660
  11. [11]Currie BJ. Marine antivenoms. Journal of Toxicology Clinical Toxicology, 2003.PMID 12807313
  12. [12]Isbister GK, Graudins A, White J, Currie BJ. Antivenom treatment in arachnidism. Journal of Toxicology Clinical Toxicology, 2003.PMID 12807312
  13. [13]Isbister GK. Failure of intramuscular antivenom in red-back spider envenoming. Emergency Medicine (Fremantle), 2002.PMID 12534488
  14. [14]Isbister GK, Jenkins S, Downes MA, et al. A randomised controlled trial and prospective cohort investigating antivenom for red-bellied black snake envenomation. Clinical Toxicology (Philadelphia), 2024.PMID 38913734
  15. [15]Cardona V, Ansotegui IJ, Ebisawa M, et al. World allergy organization anaphylaxis guidance 2020. World Allergy Organization Journal, 2020.PMID 33204386
  16. [16]Ruëff F, Bauer A, Becker S, et al. Diagnosis and treatment of Hymenoptera venom allergy: S2k Guideline of the German Society of Allergology and Clinical Immunology (DGAKI) in collaboration with the Arbeitsgemeinschaft für Berufs- und Umweltdermatologie e.V. (ABD), the Medical Association of German Allergologists (AeDA), the German Society of Dermatology (DDG), the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNOKC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Allergy and Environmental Medicine (GPA), German Respiratory Society (DGP), and the Austrian Society for Allergy and Immunology (ÖGAI). Allergologie Select, 2023.PMID 37854067
  17. [17]Cooke MW. Are current UK tetanus prophylaxis procedures for wound management optimal? Emergency Medicine Journal, 2009.PMID 19934122
  18. [18]Looke D, Dendle C. Bites (Mammalian). BMJ Clinical Evidence, 2010.PMID 21418668
  19. [19]Medeiros I, Saconato H. Antibiotic prophylaxis for mammalian bites. Cochrane Database of Systematic Reviews, 2001.PMID 11406003
  20. [20]Johnston CI, Ryan NM, Page CB, et al. The Australian Snakebite Project, 2005-2015 (ASP-20). Medical Journal of Australia, 2017.PMID 28764620
  21. [21]Isbister GK, Duffull SB, Brown SGA. A randomized controlled trial of fresh frozen plasma for treating venom-induced consumption coagulopathy in cases of Australian snakebite (ASP-18). Journal of Thrombosis and Haemostasis, 2013.PMID 23565941
  22. [22]Simard D, Bouchard V, Plourde A, et al. Factors influencing emergency department observation time following anaphylaxis: a systematic review. CJEM, 2021.PMID 33844191
  23. [23]Sturm GJ, Varga EM, Roberts G, et al. EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy, 2018.PMID 28748641
  24. [24]Liang JL, Tiwari T, Moro P, et al. Prevention of pertussis, tetanus, and diphtheria with vaccines in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recommendations and Reports, 2018.PMID 29702631
  25. [25]Isbister GK, Brown SG, Miller M, et al. A randomised controlled trial of intramuscular vs. intravenous antivenom for latrodectism — the RAVE study. QJM, 2008.PMID 18400776
  26. [26]Weber DJ, Wolfson JS, Swartz MN, et al. Pasteurella multocida infections. Report of 34 cases and review of the literature. Medicine, 1984.PMID 6371440

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Related topics

  • Snake envenomation
  • Spider and marine envenomation
  • Wound assessment and management
  • Wound closure and suturing techniques
  • The toxidrome approach and the general management of the poisoned patient
  • Sepsis and septic shock — the emergency department approach