EM · Toxicology and environmental emergencies
Snake envenomation
Also known as Australian snakebite · Elapid envenomation · Venom-induced consumption coagulopathy · VICC · Brown snake bite · Tiger snake bite
ANZ snake envenomation — elapid bites from the brown snake, tiger snake, taipan, death adder, mulga/black snake and rough-scaled snake. The four venom syndromes are venom-induced consumption coagulopathy (VICC — INR above 3, D-dimer markedly raised, fibrinogen low, from procoagulant prothrombin-activator venoms), neurotoxicity (descending paralysis — ptosis, ophthalmoplegia, bulbar palsy, respiratory failure — from presynaptic phospholipase A2 and postsynaptic three-finger toxins), rhabdomyolysis, and renal failure. First aid is the pressure immobilisation bandage. Diagnosis is clinical plus the snake venom detection kit (SVDK). Treatment is monovalent antivenom (brown snake 1 to 2 vials, tiger snake 2 to 4 vials) or polyvalent antivenom when the snake is unidentified, with adrenaline premedication and blood products only after antivenom. ACEM-primary, globally tagged.
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Meet the patient
A 45-year-old farmer is flown in from regional New South Wales three hours after a witnessed snake bite while fencing. The bite mark is barely visible and the snake was not seen clearly, but the geography favours the brown snake. He is alert, with oozing from his gum and his cannula site. The INR is unrecordable, the APTT is unrecordable, the fibrinogen is 0.3 g/L, the D-dimer is 45 mg/L, and the platelet count is 230.[1]
The two questions that decide his next hour are the two that decide every snakebite: which venom syndrome is this? (the coagulation profile and the neurology answer within the hour) and which antivenom, and how much? (the snake group, from the SVDK or the geography, answers that). Hold those two and the rest of the topic slots into place.[1]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Emergency Medicine fellowship atlas.
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- [1]Johnston CI, Ryan NM, Page CB, et al. The Australian Snakebite Project, 2005-2015 (ASP-20) Med J Aust, 2017.PMID 28764620
- [2]Isbister GK, Noutsos T, Jenkins S, et al. D-dimer testing for early detection of venom-induced consumption coagulopathy after snakebite in Australia (ASP-29) Med J Aust, 2022.PMID 35670073
- [3]Isbister GK, Isoardi KZ, Chiew AL, et al. Early cardiovascular collapse after envenoming by snakes in Australia, 2005-2020: an observational study (ASP-31) Med J Aust, 2025.PMID 40058771
- [4]Johnston CI, Ryan NM, O'Leary MA, et al. Australian taipan (Oxyuranus spp.) envenoming: clinical effects and potential benefits of early antivenom therapy - Australian Snakebite Project (ASP-25) Clin Toxicol (Phila), 2017.PMID 27903075
- [5]Brown SG, Caruso N, Borland ML, et al. Clotting factor replacement and recovery from snake venom-induced consumptive coagulopathy Intensive Care Med, 2009.PMID 19547954