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EM TopicsPaediatric respiratory distress

EM · Paediatric respiratory distress

Paediatric respiratory distress — croup, bronchiolitis and acute asthma

Also known as Croup · Laryngotracheobronchitis · Bronchiolitis · Paediatric asthma · Stridor in children · Wheeze in children

Paediatric respiratory distress — the three exam pillars of croup (upper-airway swelling, inspiratory stridor, barking cough, dexamethasone for all severities with nebulised epinephrine for moderate to severe and 2-4 h observation), bronchiolitis (clinical diagnosis, supportive care with bronchodilators and steroids lacking efficacy, high-flow rescue), and acute asthma (SABA plus anticholinergic lowering admission, early steroid, IV magnesium for refractory with scant evidence), distinguished from the can't-miss mimics of foreign body (low bronchoscopy threshold, rigid gold standard), tracheitis (febrile toxic non-responder, MSSA, 43% intubated) and pertussis/pneumonia/laryngomalacia.

high25 referencesUpdated 26 July 202616 min readSource-verified · Oct 2026

Checked against its sources on 13 Oct 2026

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Target exams

ACEMFRCEMABEMFRCPCCCFPEMEBEEM

Red flags

  • Children with severe croup are at risk for intubation — dexamethasone for all severities, nebulised epinephrine for moderate to severe, observe 2 to 4 hours
  • The febrile toxic stridulous child unresponsive to nebulised epinephrine is bacterial tracheitis — close airway monitoring plus broad-spectrum IV antibiotics; 43 percent need intubation
  • Bronchiolitis is supportive only — bronchodilators and corticosteroids lack efficacy; high-flow rescue answers 61 percent of standard-therapy failures
  • Suspected foreign-body aspiration needs prompt intervention with a low bronchoscopy threshold — rigid techniques remain the gold standard
  • Pertussis kills neonates and young infants — the cougher with apnoea is tested rapidly; pneumonia at 2-59 months takes amoxicillin first-line
On this page

Related topics

  • The sick child and paediatric resuscitation
  • Upper airway obstruction in the emergency department
  • Acute severe asthma
  • Respiratory failure (type 1 and type 2)
  • Paediatric sepsis and septic shock (the septic child in the emergency department)
  • Non-invasive ventilation in the emergency department (CPAP and BiPAP)
Study tools

Your progress

Saved on this device.

Target exams

ACEMFRCEMABEMFRCPCCCFPEMEBEEM

Red flags

  • Children with severe croup are at risk for intubation — dexamethasone for all severities, nebulised epinephrine for moderate to severe, observe 2 to 4 hours
  • The febrile toxic stridulous child unresponsive to nebulised epinephrine is bacterial tracheitis — close airway monitoring plus broad-spectrum IV antibiotics; 43 percent need intubation
  • Bronchiolitis is supportive only — bronchodilators and corticosteroids lack efficacy; high-flow rescue answers 61 percent of standard-therapy failures
  • Suspected foreign-body aspiration needs prompt intervention with a low bronchoscopy threshold — rigid techniques remain the gold standard
  • Pertussis kills neonates and young infants — the cougher with apnoea is tested rapidly; pneumonia at 2-59 months takes amoxicillin first-line
The one-line answer

Paediatric respiratory distress turns on one discriminator: stridor (upper airway) versus wheeze (lower airway). Croup — swelling of the larynx, trachea and bronchi causing inspiratory stridor and barking cough — gets dexamethasone (0.15 and 0.6 mg/kg equally effective) for every child, plus nebulised epinephrine for moderate to severe with 2 to 4 hours of observation. Bronchiolitis is supportive only — bronchodilators and corticosteroids lack efficacy. Acute asthma climbs the ladder: SABA plus anticholinergic (lower admission risk), an early steroid, and IV magnesium for the refractory attack — though evidence for benefit is scant.[1][7][10][14][15][21]

Meet the patient

It is 3am. A two-year-old is carried in on his father's lap, barking like a seal with every cough — an inspiratory stridor audible from the doorway, recessing hard, but alert and only low-grade fever. Across the bay, a four-month-old in mid-winter is wheezing and coughing, has taken half her feeds, and her mother whispers that she "forgot to breathe" twice on the way in.[1]

The toddler has croup — the commonest stridor of childhood; the infant has bronchiolitis — the commonest wheeze of infancy. The single question that orders everything you do next is the one this whole topic turns on: is the obstruction above or below the glottis — stridor or wheeze? Hold that question, then add a second: how hard is the child working, and is it getting better or worse?[1]

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References25ShowHide
  1. [1]Smith DK, McDermott AJ, Sullivan JF. Croup: Diagnosis and Management Am Fam Physician, 2018.PMID 29763253
  2. [2]Bjornson CL, Klassen TP, Williamson J, et al. A randomized trial of a single dose of oral dexamethasone for mild croup N Engl J Med, 2004.PMID 15385657
  3. [3]Russell KF, Liang Y, O'Gorman K, et al. Glucocorticoids for croup Cochrane Database Syst Rev, 2011.PMID 21249651
  4. [4]Bjornson C, Russell K, Vandermeer B, et al. Nebulized epinephrine for croup in children Cochrane Database Syst Rev, 2013.PMID 24114291
  5. [5]Ralston SL, Lieberthal AS, Meissner HC, et al. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis Pediatrics, 2014.PMID 25349312
  6. [6]Franklin D, Babl FE, Schibler AS, et al. A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis N Engl J Med, 2018.PMID 29562151
  7. [7]Griffiths B, Ducharme FM. Combined inhaled anticholinergics and short-acting beta2-agonists for initial treatment of acute asthma in children Cochrane Database Syst Rev, 2013.PMID 23966133
  8. [8]Cole S, Wilkinson S, Kubba H Rigid bronchoscopy is the gold standard management of inhaled foreign bodies in children: myth or maxim? Breathe (Sheff), 2026.PMID 42344147
  9. [9]Akhavan M Ear, Nose, Throat: Beyond Pharyngitis: Retropharyngeal Abscess, Peritonsillar Abscess, Epiglottitis, Bacterial Tracheitis, and Postoperative Tonsillectomy Emerg Med Clin North Am, 2021.PMID 34215408
  10. [10]Schuh S, O'Shea S, Freedman SB, et al. Magnesium in acute pediatric asthma in the emergency department (MAGICIAN)-A multicentre randomized controlled clinical trial protocol PLoS One, 2026.PMID 42234723
  11. [11]Cherry JD. Adult pertussis in the pre- and post-vaccine eras: lifelong vaccine-induced immunity? Expert Rev Vaccines, 2014.PMID 24985069
  12. [12]Harris M, et al. British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011 Thorax, 2011.PMID 21903691
  13. [13]Hazkani I, et al. Congenital Laryngomalacia: Pathophysiology, Clinical Spectrum, and Holistic Management Otolaryngol Clin North Am, 2026.PMID 41963137
  14. [14]Bjornson CL, Johnson DW Croup. Lancet (London, England), 2008.PMID 18295000
  15. [15]Chub-Uppakarn S, Sangsupawanich P A randomized comparison of dexamethasone 0.15 mg/kg versus 0.6 mg/kg for the treatment of moderate to severe croup. International journal of pediatric otorhinolaryngology, 2007.PMID 17208307
  16. [16]Khalid A, Flesher S, Martins Shehan TS Low-dose (0.15 mg/kg) versus high-dose (0.6 mg/kg) dexamethasone for pediatric croup: a meta-analysis with trial sequential analysis of RCTs. Frontiers in pediatrics, 2026.PMID 42698708
  17. [17]Casazza G, Graham ME, Nelson D, et al. Pediatric Bacterial Tracheitis-A Variable Entity: Case Series with Literature Review. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2019.PMID 30348058
  18. [18]Purcell R, Heininger U, Buttery J Fifteen-minute consultation: A guide to pertussis. Archives of disease in childhood. Education and practice edition, 2025.PMID 40037719
  19. [19]Kline JM, Lewis WD, Smith EA, et al. Pertussis: a reemerging infection. American family physician, 2013.PMID 24364571
  20. [20]Castro-Rodriguez JA, Rodriguez-Martinez CE, Sossa-Briceño MP Principal findings of systematic reviews for the management of acute bronchiolitis in children. Paediatric respiratory reviews, 2015.PMID 25636596
  21. [21]Joseph MM, Edwards A Acute bronchiolitis: assessment and management in the emergency department. Pediatric emergency medicine practice, 2019.PMID 31557431
  22. [22]Kundu S, Das S, Medhagopal RG An Update on WHO Recommendations on Childhood Pneumonia and Diarrhea (2024). Indian pediatrics, 2025.PMID 40839064
  23. [23]Mathur S, Fuchs A, Bielicki J, et al. Antibiotic use for community-acquired pneumonia in neonates and children: WHO evidence review. Paediatrics and international child health, 2018.PMID 29790844
  24. [24]Ciarallo L, Sauer AH, Shannon MW Intravenous magnesium therapy for moderate to severe pediatric asthma: results of a randomized, placebo-controlled trial. The Journal of pediatrics, 1996.PMID 8969721
  25. [25]Craig SS, Dalziel SR, Powell CV, et al. Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews. The Cochrane database of systematic reviews, 2020.PMID 32767571
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Related topics

  • The sick child and paediatric resuscitation
  • Upper airway obstruction in the emergency department
  • Acute severe asthma
  • Respiratory failure (type 1 and type 2)
  • Paediatric sepsis and septic shock (the septic child in the emergency department)
  • Non-invasive ventilation in the emergency department (CPAP and BiPAP)