Anaes SAQs · TIVA & target-controlled infusion
The compartment models and the TCI pharmacokinetics
Primary — the central/fast/slow compartments; the Vd, the CL, the intercompartmental; the Marsh (weight-based), the Schnider (age/weight/height/LBM), the Eleveld (large dataset), the Minto (remifentanil); the ke0.
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Target exams
ANZCAFRCAABAEDAIC
Prompt
Describe the 3-compartment model and the pharmacokinetic models used for the propofol and the remifentanil TCI.
Question
Describe the 3-compartment model and the pharmacokinetic models used for the propofol and the remifentanil TCI.
[1]References2ShowHide
- [1]Keresztes M, et al. Target-Controlled Infusion for Caesarean Delivery Under General Anesthesia: From Conventional Pharmacokinetic Models to Physiologically Based Pharmacokinetic Modeling. Life, 2026.PMID 42195295
- [4]Taplin CF, et al. Real-time propofol monitoring. Anaesth Intensive Care, 2026.PMID 42290030