Anaes SAQs · Applied cardiovascular & respiratory physiology
The coronary and cerebral circulations
Primary — coronary anatomy, diastolic flow, coronary perfusion pressure = DBP minus LVEDP, near-maximal O2 extraction requiring flow-matched demand; cerebral autoregulation plateau (50 to 150 mmHg), right shift in chronic HTN, CO2 reactivity, CPP = MAP minus ICP.
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ANZCAFRCAABAEDAIC
Prompt
Compare the coronary and cerebral circulations. Explain why coronary blood flow occurs predominantly in diastole, and describe the autoregulation and carbon dioxide reactivity of the cerebral circulation.
Question
Compare the coronary and cerebral circulations. Explain why coronary blood flow occurs predominantly in diastole, and describe the autoregulation and carbon dioxide reactivity of the cerebral circulation.[1][5]
References4ShowHide
- [1]Soule Z, et al. Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices. J Stroke, 2026.PMID 42237618
- [5]Bottiroli M, et al. Perioperative Management of Patients With Durable and Temporary Left Ventricular Assist Devices Undergoing Non-Cardiac Surgery: A Comprehensive Review. J Cardiothorac Vasc Anesth, 2026.PMID 42350177
- [6]Shah S, et al. Effects of Pharmacologic, Non-Pharmacologic, and Exercise-Based Interventions on Coronary Collateral Circulation: A Scoping Review. Cardiology, 2026.PMID 42319860
- [3]Murakami S, et al. In Reply to: Comment on "Effect of intraoperative position on the zero flow pressure of the cerebral circulation under propofol anesthesia: a prospective observational study". J Anesth, 2026.PMID 42313123