Anaes SAQs · Applied cardiovascular & respiratory physiology
The cardiac conduction system and the ECG
Primary — SA-node pacemaker (funny current), AV-node delay and concealed conduction, His-Purkinje rapid ventricular activation, gap-junction cell-to-cell conduction; ECG correlation (P, PR, QRS, T); arrhythmia mechanisms (automaticity, re-entry, triggered activity).
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Prompt
Describe the cardiac conduction system and relate each structure to the corresponding feature of the surface ECG. Outline the three mechanisms by which arrhythmia arises.
Question
Describe the cardiac conduction system and relate each structure to the corresponding feature of the surface ECG. Outline the three mechanisms by which arrhythmia arises.
[1]References4ShowHide
- [1]Fujiu K, et al. Cardiac conduction: gap junction biology. Circ J, 2026.PMID 41535054
- [2]Saponaro A. Structure mirroring function: What's the 'matter' with the funny current? J Physiol, 2026.PMID 40013960
- [3]Copier JS, et al. HCN4 in the atrioventricular node. Heart Rhythm, 2025.PMID 39988103
- [4]Fan W, et al. HCN4 and arrhythmias: Insights into base mutations. Mutat Res Rev, 2025.PMID 39922561