Phys Clinical Cases · infectious
Bloodstream Infections and Infective Endocarditis — DCE Clinical Case
DCE short-case station: 'Examine this patient for signs of infective endocarditis' — a systematic examination routine for peripheral stigmata and the precordium, with presentation template and discussion.
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Target exams
The systematic routine
End of the bed first. Look before touching: fever chart and observations at the foot, oxygen or monitoring, visible distress, cachexia from weeks of illness, and the clues to source and severity — intravenous lines, a PICC, a dialysis catheter, track marks suggesting injecting drug use [2].
Hands — the highest-yield peripheral examination. Splinter haemorrhages under the nails, Janeway lesions (non-tender macules on palms and thenar eminences), Osler nodes (tender nodules in the finger pulp), clubbing, and peripheral perfusion — a cold pulseless finger here is an embolus, and that is a vascular Duke criterion [1] [2].
Arms and access sites. Dialysis fistulae, old and new puncture sites, PICC or central line sites with any erythema — each is a potential portal of entry and changes the organism list [2].
Face, eyes and mouth. Conjunctival pallor and petechiae; then say the words — "I would examine the fundi for Roth spots" (retinal haemorrhages with pale centres). Inspect the teeth and gums: the dental state is both a source and a prevention conversation, and palatal petechiae count [1] [2].
The precordium. Inspect for a median sternotomy scar, a CIED pocket (and any erythema over it), then palpate and auscultate systematically. You are listening for regurgitant murmurs: the early diastolic murmur of aortic regurgitation at the left sternal edge in expiration, and the pansystolic murmur of mitral regurgitation at the apex radiating to the axilla — and for the mechanical clicks of a prosthetic valve. A new regurgitant murmur is itself a major Duke criterion [1].
Complete the circuit. Sacral and peripheral oedema and auscultated lung bases for heart failure (the surgical urgency), abdominal palpation for splenomegaly, a urine dipstick for haematuria (glomerulonephritis — an immunologic criterion), and a quick neurological screen for embolic deficits [1] [2].
Close the loop. "To complete my assessment I would review the temperature chart, the blood culture results and the echocardiogram" [3].
You have read the opening of this clinical case. The complete unit — every section and its primary-source references — is part of the Physician Medicine fellowship atlas.
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- [1]Fowler VG, Durack DT, Selton-Suty C, et al. The 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis: Updating the Modified Duke Criteria Clin Infect Dis, 2023.PMID 37138445
- [2]Baddour LM, Wilson WR, Bayer AS, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association Circulation, 2015.PMID 26373316
- [3]Lee A, Mirrett S, Reller LB, et al. Detection of bloodstream infections in adults: how many blood cultures are needed? J Clin Microbiol, 2007.PMID 17881544
- [4]Delgado V, Ajmone Marsan N, de Waha S, et al. 2023 ESC Guidelines for the management of endocarditis Eur Heart J, 2023.PMID 37622656