Paeds · respiratory-sleep-and-airway
Pleural effusion and empyema
Also known as Parapneumonic effusion · Complicated parapneumonic effusion · Empyema thoracis · Pleural infection · Pyothorax
Fellowship guide to paediatric pleural effusion and empyema: the parapneumonic fluid that turns a child's pneumonia into persistent fever and pleuritic pain; Light's criteria and the exudative, fibrinopurulent and organising stages; ultrasound as the pivotal investigation; antibiotics for all, chest drain with intrapleural fibrinolytics or primary VATS for empyema; the excellent long-term prognosis; and the ANZ, UK and North American guideline differences.
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Overview & Definition
Picture the four-year-old admitted three days ago with a lobar pneumonia who should be turning the corner but is not: she is still spiking fevers to 39.5 °C, she is breathing fast, she flinches when she coughs, and the intern notices her breath sounds are now stony-dull at the right base. That failure to improve, not any single dramatic sign, is the classic way a parapneumonic effusion announces itself, and recognising it early is what turns a long, complicated admission into a treatable one. [1] [2]
A pleural effusion is simply an abnormal collection of fluid in the pleural space, the potential space between the visceral pleura covering the lung and the parietal pleura lining the chest wall. In children the overwhelming cause is a parapneumonic effusion — fluid that gathers next to a bacterial pneumonia — and when the fluid becomes infected and thick with pus it is called an empyema. [1] [9]
Why this matters at fellowship level is that empyema is not rare and has been rising: it is a predictable, recognisable complication of a common illness, it responds well to the right treatment, and the marks are earned by spotting the child who is not improving, choosing ultrasound over a plain film, and knowing when antibiotics alone will not be enough. [8] [2]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship atlas.
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- [1]Balfour-Lynn IM, Abrahamson E, Cohen G, et al. BTS guidelines for the management of pleural infection in children. Thorax, 2005.PMID 15681514
- [2]Islam S, Calkins CM, Goldin AB, et al. The diagnosis and management of empyema in children: a comprehensive review from the APSA Outcomes and Clinical Trials Committee. J Pediatr Surg, 2012.PMID 23164006
- [3]Thomson AH, Hull J, Kumar MR, et al. Randomised trial of intrapleural urokinase in the treatment of childhood empyema. Thorax, 2002.PMID 11923554
- [4]Sonnappa S, Cohen G, Owens CM, et al. Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. Am J Respir Crit Care Med, 2006.PMID 16675783
- [5]St Peter SD, Tsao K, Spilde TL, et al. Thoracoscopic decortication vs tube thoracostomy with fibrinolysis for empyema in children: a prospective, randomized trial. J Pediatr Surg, 2009.PMID 19159726
- [6]Redden MD, Chin TY, van Driel ML. Surgical versus non-surgical management for pleural empyema. Cochrane Database Syst Rev, 2017.PMID 28304084
- [7]Light RW, Macgregor MI, Luchsinger PC, et al. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med, 1972.PMID 4642731
- [8]Grijalva CG, Nuorti JP, Zhu Y, et al. Increasing incidence of empyema complicating childhood community-acquired pneumonia in the United States. Clin Infect Dis, 2010.PMID 20166818
- [9]Byington CL, Spencer LY, Johnson TA, et al. An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations. Clin Infect Dis, 2002.PMID 11797168
- [10]Griffith D, Boal M, Rogers T. Evolution of practice in the management of parapneumonic effusion and empyema in children. J Pediatr Surg, 2018.PMID 28781127
- [11]Roberts ME, Rahman NM, Maskell NA, et al. British Thoracic Society Guideline for pleural disease. Thorax, 2023.PMID 37553157