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O&G SAQsGynaecological health — sexually transmitted infections

O&G SAQs · Gynaecological health — sexually transmitted infections

STI screening and management — structured SAQ (15 marks)

FRANZCOG-format structured SAQ on STI screening and management: the structured panel (NAAT, syphilis serology, HIV, hepatitis B and C, cervical screen), the verbatim first-line chlamydia dose with the pregnancy switch to azithromycin, the partner notification framework including PDPT and trace-back windows, and the retest-at-3-months policy. Per-sub-part marking rubric included.

15 marks20 min3 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOG
Prompt
A 23-year-old woman, para 0, presents with a 2-week history of postcoital bleeding and a yellowish vaginal discharge. She has a new male sexual partner of 3 months. She is not pregnant. On speculum examination the cervix is friable with a mucopurulent discharge; on bimanual examination there is mild cervical motion tenderness but no adnexal tenderness or masses. (a) Outline the structured STI screening panel you will send today, and the rationale for each test. (4 marks) (b) The chlamydia NAAT is positive; gonorrhoea NAAT is negative; syphilis, HIV and hepatitis serology are negative. State your first-line treatment with drug, dose, route and duration, and explain how the regimen would change if she were pregnant. (4 marks) (c) Outline the partner notification process you will initiate in this consultation, including the trace-back window and any expedited/partner-delivered therapy options. (4 marks) (d) Describe your follow-up plan over the next 12 months, including any retesting and sexual abstinence counselling. (3 marks)

How this SAQ is marked

Marks come from running the full panel (not a single NAAT), the verbatim first-line chlamydia dose with the pregnancy switch, the partner notification framework with the correct trace-back window and the PDPT option, and the retest-at-3-months policy. [1]

Reveal model answer and mark schemeShowHide

(a) The structured STI panel (4 marks)

One mark per correctly named test, maximum four. [1][2]

  • Chlamydia and gonorrhoea NAAT — self-collected vaginal swab is the test of choice; first-pass urine is acceptable; add anorectal and pharyngeal swabs based on reported exposures. The friable mucopurulent cervix strongly suggests chlamydia or gonorrhoea.[1]
  • Syphilis serology — combined treponemal (CMIA or EIA) plus non-treponemal (RPR) testing; the laboratory runs the algorithm.[1]
  • HIV serology — antigen/antibody combination assay; window period 2 to 6 weeks; offer PrEP if ongoing risk.[1]
  • Hepatitis B (HBsAg, anti-HBs, anti-HBc) and hepatitis C antibody — one-time HCV testing for every adult; vaccinate against HBV if non-immune.[1]
  • Cervical screen (HPV plus LBC co-test) — performed if due; PCB in a symptomatic woman warrants cervical screening regardless of recall status, because screening is not diagnostic.[1][5]

(b) First-line chlamydia treatment, with the pregnancy switch (4 marks)

Two marks for the correct non-pregnant regimen, two marks for the pregnancy switch and rationale. [1][4]

  • Non-pregnant first-line regimen: doxycycline 100 mg orally twice daily for 7 days. Doxycycline is now preferred over azithromycin because it outperforms azithromycin for anorectal chlamydia in women, which is common and often unrecognised.[1][4]
  • Alternative (non-pregnant): azithromycin 1 g orally as a single dose — only when adherence to seven days is unlikely and anorectal infection is less likely.
  • Pregnancy switch: azithromycin 1 g orally as a single dose is the recommended regimen in pregnancy; doxycycline is contraindicated because of fetal tooth discoloration.[1]
  • Advise no sexual contact for 7 days after starting treatment, or until the course is complete and symptoms resolved, whichever is later.[1]

(c) Partner notification and PDPT (4 marks)

One mark per point, maximum four. [1][3]

  • The diagnosing doctor is responsible for initiating and documenting the partner notification discussion in the same consultation.
  • Chlamydia trace-back window: at least 6 months before the diagnosis, or to the last negative test.[1]
  • Three notification strategies: patient referral (index informs partners), provider referral (clinic contacts partners without naming the index), and patient-delivered partner therapy (PDPT) — the index delivers a prescription or packaged medication to their partner. PDPT is approved in Victoria, NSW and the NT for heterosexual index patients with anogenital or oropharyngeal chlamydia where partners are unlikely to attend for testing.[1][3]
  • Notification to the state or territory health department is statutory — chlamydia is a notifiable disease under the relevant Public Health Act.[1]

(d) Follow-up and retesting (3 marks)

One mark per point. [1]

  • Test of cure is not routinely recommended for non-pregnant patients treated with the recommended regimen (repeat NAAT at 4 weeks after treatment is only needed in pregnancy, where the test of cure is recommended).[1]
  • Retest at 3 months after treatment regardless of whether the partners were treated, because reinfection is common — schedule the follow-up at the time of treatment.[1]
  • Counsel sexual abstinence for 7 days after the start of treatment, until symptoms resolve, and until all sex partners from the last 6 months have been tested and treated if necessary.[1]
Obstetrics & Gynaecology Pro

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You have read the opening of this SAQ. The complete unit — every section and its primary-source references — is part of the Obstetrics & Gynaecology fellowship library.

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References5ShowHide
  1. [1]Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, Reno H, Zenilman JM, Bolan GA Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep, 2021.PMID 34292926
  2. [2]Cantor A, Dana T, Griffin JC, Nelson HD, Weeks C Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA, 2021.PMID 34519797
  3. [3]Ferreira A, Young T, Mathews C, Zunza M, Low N Strategies for partner notification for sexually transmitted infections, including HIV. Cochrane Database Syst Rev, 2013.PMID 24092529
  4. [4]Peuchant O, Lhomme E, Martinet P, Grob A, Baïta D Doxycycline versus azithromycin for the treatment of anorectal Chlamydia trachomatis infection in women concurrent with vaginal infection (CHLAZIDOXY study): a multicentre, open-label, randomised, controlled trial. Lancet Infect Dis, 2022.PMID 35550262
  5. [5]Bhatla N, Puri K, Joseph E, Kriplani A, Iyer VK, Sreenivas V Association of Chlamydia trachomatis infection with human papillomavirus (HPV) & cervical intraepithelial neoplasia - a pilot study. Indian J Med Res, 2013.PMID 23640561
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