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ICU TopicsResuscitation

ICU · Resuscitation

Acute limb compartment syndrome

Also known as Compartment syndrome · Fasciotomy · The 6 Ps · Delta pressure · Volkmann contracture · Two-incision fasciotomy · Crush syndrome · Perfusion pressure

Acute limb compartment syndrome is elevated pressure within a fascial compartment causing ischaemia and necrosis of muscles and nerves. Causes: fracture (1 — tibial shaft, forearm), crush injury, burns (circumferential), prolonged immobility, reperfusion injury (post-vascular repair), tight casts/dressings, bleeding into compartment (anticoagulated). The 6 Ps: Pain (disproportionate, worse on passive stretch — the EARLIEST and most sensitive sign), Pallor, Paraesthesia, Paralysis, Pulselessness (LATE — absence of pulse means it's too late), Poikilothermia. Diagnosis: clinical + compartment pressure measurement (delta pressure = diastolic BP - compartment pressure <30 mmHg = positive). Treatment: EMERGENT FASCIOTOMY (within 6 hours to prevent irreversible necrosis). Untreated → Volkmann ischaemic contracture, amputation, rhabdomyolysis, renal failure.

high12 referencesUpdated 26 July 202614 min readVerification in progress

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CICMFFICMEDIC

Red flags

  • Pain OUT OF PROPORTION to injury + worse on passive stretch = compartment syndrome until proven otherwise
  • Pulselessness is a LATE sign — if pulse is absent, damage is irreversible
  • Delta pressure (DBP - compartment pressure) &lt;30 mmHg = fasciotomy needed
  • Fasciotomy within 6 hours — irreversible necrosis after 6-8 hours
  • Increasing analgesia requirement in a traumatized limb is a RED FLAG for compartment syndrome
  • Do NOT wait for all 6 Ps — by the time pulse is lost, the window for limb salvage has closed
  • A patient on anticoagulants with limb pain post-injury is high-risk for bleed into compartment
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Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

CICMFFICMEDIC

Red flags

  • Pain OUT OF PROPORTION to injury + worse on passive stretch = compartment syndrome until proven otherwise
  • Pulselessness is a LATE sign — if pulse is absent, damage is irreversible
  • Delta pressure (DBP - compartment pressure) &lt;30 mmHg = fasciotomy needed
  • Fasciotomy within 6 hours — irreversible necrosis after 6-8 hours
  • Increasing analgesia requirement in a traumatized limb is a RED FLAG for compartment syndrome
  • Do NOT wait for all 6 Ps — by the time pulse is lost, the window for limb salvage has closed
  • A patient on anticoagulants with limb pain post-injury is high-risk for bleed into compartment
In one line

Compartment syndrome = elevated fascial pressure → muscle/nerve ischaemia. 6 Ps: Pain (disproportionate, worse on passive stretch — EARLIEST sign), Pallor, Paraesthesia, Paralysis, Pulselessness (LATE — too late), Poikilothermia. Delta pressure (DBP - compartment pressure) <30 = positive. Treatment: EMERGANT FASCIOTOMY within 6h. Causes: fracture (#1), crush, burns, reperfusion, tight dressings. Untreated → Volkmann ischaemic contracture, amputation, rhabdomyolysis, renal failure.

[8]

Meet the patient

A 25-year-old man is admitted after a high-energy tibial fracture, in a below-knee cast. At 2am the nurse calls you: his pain is severe and escalating despite the PCA, and the leg feels tense. Pulses are present. The foundation doctor thinks it is just the fracture pain. It is not — this is compartment syndrome, and the fasciotomy happens tonight.[1]

The diagnosis is clinical, made at the bedside, and the two questions that decide the limb are the two every candidate must answer: is the pain out of proportion and worse on passive stretch? And is the delta pressure under 30? Hold those two and the rest follows — the fasciotomy within 6 hours, the four compartments released, the wound left open.[3]

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References12ShowHide
  1. [1]von Keudell AG, Weaver MJ, Appleton PT, et al. Diagnosis and treatment of acute extremity compartment syndrome. Lancet (London, England), 2015.PMID 26460664
  2. [2]Schmidt AH Acute compartment syndrome. Injury, 2017.PMID 28449851
  3. [3]McQueen MM, Court-Brown CM. Compartment monitoring in tibial fractures. The pressure threshold for decompression. Journal of Bone and Joint Surgery (British), 1996.PMID 8898137
  4. [4]McQueen MM, Duckworth AD, Aitken SA, Court-Brown CM. The estimated sensitivity and specificity of compartment pressure monitoring for acute compartment syndrome. Journal of Bone and Joint Surgery (American), 2013.PMID 23595064
  5. [5]McQueen MM, Duckworth AD, Aitken SA, Sharma RA, Court-Brown CM. Predictors of compartment syndrome after tibial fracture. Journal of Orthopaedic Trauma, 2015.PMID 25882967
  6. [6]McQueen MM, Christie J, Court-Brown CM. Acute compartment syndrome in tibial diaphyseal fractures. Journal of Bone and Joint Surgery (British), 1996.PMID 8898136
  7. [7]Whitesides TE, Haney TC, Morimoto K, Harada H. Tissue pressure measurements as a determinant for the need of fasciotomy. Clinical Orthopaedics and Related Research, 1975.PMID 1192674
  8. [8]Owen CA, Mubarak SJ, Hargens AR, et al. Intramuscular pressures with limb compression. Clarification of the pathogenesis of the drug-induced muscle-compartment syndrome. New England Journal of Medicine, 1979.PMID 431646
  9. [9]Mubarak SJ, Owen CA. Double-incision fasciotomy of the leg for decompression in compartment syndromes. Journal of Bone and Joint Surgery (American), 1977.PMID 15455478
  10. [10]Zimmerman JL, Shen MC. Rhabdomyolysis. Chest, 2013.PMID 24008958
  11. [11]Chavez LO, Leon M, Einav S, Varon J. Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice. Critical care (London, England), 2016.PMID 27301374
  12. [12]Kirkpatrick AW, Roberts DJ, De Waele J, et al. Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive care medicine, 2013.PMID 23673399

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