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ICU TopicsGI/Nutrition

ICU · GI/Nutrition

Intra-abdominal hypertension and abdominal compartment syndrome

Also known as Intra-abdominal hypertension (IAH) · Abdominal compartment syndrome (ACS) · Intra-abdominal pressure (IAP) · Abdominal perfusion pressure (APP) · Surgical decompression

Intra-abdominal hypertension (IAH) is sustained intra-abdominal pressure 12 mmHg. Abdominal compartment syndrome (ACS) is sustained IAP 20 mmHg with NEW ONSET organ failure (kidney, respiratory, cardiovascular). Causes: abdominal trauma/surgery, massive fluid resuscitation, pancreatitis, ileus, peritonitis, burns. Measurement: bladder pressure (gold standard). Effects of raised IAP: renal failure (venous congestion, reduced perfusion), respiratory failure (elevated diaphragm, reduced compliance, high ventilator pressures), cardiovascular (reduced venous return, reduced cardiac output), intestinal ischaemia, raised intracranial pressure. Treatment: decompressive laparotomy for ACS. Prevent: avoid excessive fluid resuscitation, nasogastric decompression, prokinetics.

medium19 referencesUpdated 20 Aug 20268 min readVerification in progress

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CICMFFICMEDIC

Red flags

  • ACS = IAP >20 mmHg + new organ failure — surgical emergency. Decompressive laparotomy required
  • Unexplained oliguria + high ventilator pressures + metabolic acidosis = measure bladder pressure
  • Over-resuscitation with crystalloid is the #1 cause of secondary ACS — avoid excessive fluids
  • Raised IAP increases intracranial pressure — important in TBI patients with abdominal injuries
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Practise this topic8 MCQs with explanations

Target exams

CICMFFICMEDIC

Red flags

  • ACS = IAP >20 mmHg + new organ failure — surgical emergency. Decompressive laparotomy required
  • Unexplained oliguria + high ventilator pressures + metabolic acidosis = measure bladder pressure
  • Over-resuscitation with crystalloid is the #1 cause of secondary ACS — avoid excessive fluids
  • Raised IAP increases intracranial pressure — important in TBI patients with abdominal injuries
In one line

Intra-abdominal hypertension (IAH) is a sustained intra-abdominal pressure (IAP) over 12 mmHg; abdominal compartment syndrome (ACS) is a sustained IAP over 20 mmHg with new organ failure. Measure bladder pressure (the gold standard). The organs that fail are the kidney first (oliguria, anuria), then the lung (high airway pressures), then the circulation (low cardiac output), with raised intracranial pressure in the multiply-injured. Management is a ladder — decompress hollow viscera, drain fluid, optimise abdominal perfusion pressure (APP = MAP minus IAP, target over 60) — escalating to decompressive laparotomy for established ACS. The dominant preventable cause is the crystalloid you gave yourself.

[1]

Meet the patient

A 62-year-old man is in ICU on day 2 after an emergency open repair of a ruptured abdominal aortic aneurysm. He had 8 units of red cells, 6 of plasma, and 6 litres of crystalloid in theatre. Now he is oliguric at 8 mL an hour despite two doses of furosemide, his abdomen is tense, his peak airway pressure has climbed from 28 to 46 cmH2O, and his bladder pressure is 30 mmHg.[2][18]

Two questions decide his next hour, and they are the two that decide every case of suspected ACS: is the pressure over 20 with new organ failure? and have you, in chasing his blood pressure, made the compartment tighter? Hold those two and the management ladder below slots into place.[3]

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References19ShowHide
  1. [1]Kirkpatrick AW, Roberts DJ, De Waele J, et al. Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome Intensive Care Med, 2013.PMID 23673399
  2. [2]Malbrain ML, Cheatham ML, Kirkpatrick A, et al. Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions Intensive Care Med, 2006.PMID 16967294
  3. [3]Nasa P, Chanchalani G, Juneja D, et al. Surgical decompression for the management of abdominal compartment syndrome with severe acute pancreatitis: A narrative review World J Gastrointest Surg, 2023.PMID 37901738
  4. [4]Malbrain ML, Chiumello D, Pelosi P, et al. Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study Crit Care Med, 2005.PMID 15699833
  5. [5]Cheatham ML, White MW, Sagraves SG, et al. Abdominal perfusion pressure: a superior parameter in the assessment of intra-abdominal hypertension J Trauma, 2000.PMID 11038078
  6. [6]Cheatham ML, Safcsak K Percutaneous catheter decompression in the treatment of elevated intraabdominal pressure Chest, 2011.PMID 21903735
  7. [7]Regli A, Pelosi P, Malbrain MLNG Ventilation in patients with intra-abdominal hypertension: what every critical care physician needs to know Ann Intensive Care, 2019.PMID 31025221
  8. [8]Regli A, Reintam Blaser A, De Keulenaer B, et al. Intra-abdominal hypertension and hypoxic respiratory failure together predict adverse outcome - A sub-analysis of a prospective cohort J Crit Care, 2021.PMID 33906106
  9. [9]Lozada MJ, Goyal V, Levin D, et al. Management of peripartum intra-abdominal hypertension and abdominal compartment syndrome Acta Obstet Gynecol Scand, 2019.PMID 31070780
  10. [10]Nasa P, Wise RD, Smit M, et al. International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome World J Emerg Surg, 2024.PMID 39609850
  11. [11]Radenkovic DV, Bajec D, Ivancevic N, et al. Decompressive laparotomy with temporary abdominal closure versus percutaneous puncture with placement of abdominal catheter in patients with abdominal compartment syndrome during acute pancreatitis: background and design of multicenter, randomised, controlled study BMC Surg, 2010.PMID 20624281
  12. [12]Malbrain ML, Deeren DH Effect of bladder volume on measured intravesical pressure: a prospective cohort study Crit Care, 2006.PMID 16934130
  13. [13]Cheatham ML, De Waele JJ, De Laet I, et al. The impact of body position on intra-abdominal pressure measurement: a multicenter analysis Crit Care Med, 2009.PMID 19487946
  14. [14]De Laet I, Hoste E, Verholen E, De Waele JJ The effect of neuromuscular blockers in patients with intra-abdominal hypertension Intensive Care Med, 2007.PMID 17594072
  15. [15]Malbrain ML, Ameloot K, Gillebert C, Cheatham ML Cardiopulmonary monitoring in intra-abdominal hypertension Am Surg, 2011.PMID 21944448
  16. [16]Al-Dorzi HM, Tamim HM, Rishu AH, et al. Intra-abdominal pressure and abdominal perfusion pressure in cirrhotic patients with septic shock Ann Intensive Care, 2012.PMID 22873420
  17. [17]Cheatham ML, Safcsak K Is the evolving management of intra-abdominal hypertension and abdominal compartment syndrome improving survival? Crit Care Med, 2010.PMID 20095067
  18. [18]Djavani K, Wanhainen A, Björck M Intra-abdominal hypertension and abdominal compartment syndrome following surgery for ruptured abdominal aortic aneurysm Eur J Vasc Endovasc Surg, 2006.PMID 16458547
  19. [19]De Keulenaer BL, De Waele JJ, Powell B, Malbrain ML What is normal intra-abdominal pressure and how is it affected by positioning, body mass and positive end-expiratory pressure? Intensive Care Med, 2009.PMID 19242675

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