ICU SAQs · Oxygen & gas exchange
High-flow nasal cannula and the oxygen-target question
A CICM Second-Part SAQ on the HFNC (FLORALI — reduced intubation rate) and the oxygen-target question (Chu 2018 — liberal oxygen increases mortality; the conservative target of 92 to 96 per cent, 88 to 92 for COPD).
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Prompt
Critically appraise the use of the high-flow nasal cannula in acute hypoxaemic respiratory failure, and the optimal peripheral oxygen saturation target in the critically ill.
Question
Critically appraise the use of the high-flow nasal cannula in acute hypoxaemic respiratory failure, and the optimal peripheral oxygen saturation target in the critically ill.
[1]References3ShowHide
- [1]Frat JP, Thille AW, Mercat A, et al. High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure (FLORALI). New England Journal of Medicine, 2015.PMID 25981908
- [2]Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy. Lancet, 2018.PMID 29726345
- [3]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.