ICU SAQs · Oxygen & gas exchange
Oxygen delivery, consumption and the Fick principle
A CICM First-Part basic-science SAQ on DO2 = CO × CaO2; the CaO2 (Hb × saturation × 1.34 + dissolved); the Fick principle VO2 = CO × (CaO2 − CvO2); the extraction ratio; and the ScvO2 as the surrogate of the delivery-consumption balance.
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Prompt
Derive global oxygen delivery from first principles. Explain the Fick principle and the extraction ratio, and how the venous oxygen saturation reflects the delivery-consumption balance.
Question
Derive global oxygen delivery from first principles. Explain the Fick principle and the extraction ratio, and how the venous oxygen saturation reflects the delivery-consumption balance.[1]
References2ShowHide
- [1]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
- [2]Marino PL The ICU Book. 4th edition, Lippincott Williams & Wilkins, 2014.