EM · Procedural & diagnostic ED skills
Lumbar puncture in the emergency department
Also known as Lumbar puncture · LP · Spinal tap · Cerebrospinal fluid sampling · CSF analysis
Lumbar puncture in the ED — the indications (suspected meningitis or encephalitis, subarachnoid haemorrhage after a negative CT, demyelinating disease — multiple sclerosis, CIDP, Guillain-Barre, and the therapeutic uses — idiopathic intracranial hypertension, cryptococcal meningitis, intrathecal drug delivery), the contraindications (raised intracranial pressure with papilloedema or a focal deficit, coagulopathy with an INR over 1.4 or platelets under 50, overlying skin infection), the anatomy (the conus at L1/L2, the dural sac at S2, Tuffier's line crossing L4), the technique (L3/L4 or L4/L5, midline, the bevel parallel to the longitudinal dural fibres, the atraumatic over the cutting needle), the CSF interpretation (bacterial — high neutrophils, low glucose; viral — lymphocytes, normal glucose; TB — very low glucose, very high protein; SAH — xanthochromia and uniform red cells), and the post-dural puncture headache (atraumatic needle halves it; caffeine and the epidural blood patch treat it). ACEM-primary, globally tagged.
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8 MCQs with explanations
Target exams
Red flags
Related topics
- Meningitis and encephalitis (emergency department diagnosis and management)
- Subarachnoid haemorrhage
- Red-flag headache (approach)
- Raised intracranial pressure
- Guillain-Barré syndrome and myasthenia gravis
- Procedural sedation in the emergency department
- Local anaesthesia and topical agents
- Seizures and the first fit
Meet the patient
A 34-year-old man arrives with 24 hours of fever, severe headache, photophobia and neck stiffness. His GCS is 14, there is no focal deficit, no papilloedema, the INR is 1.0 and the platelets 220. The Ottawa SAH rule is not met. You decide to perform a lumbar puncture.[1]
The two questions an examiner will press are the two that run this station: when do you image before the puncture? (the CT-first criteria) and how do you read the four tubes once they are drawn? (the cell count, glucose, protein, and the tube 1 to tube 4 red-cell comparison). Hold those two questions and the whole topic slots into place.[1]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Emergency Medicine fellowship atlas.
References9Show ledgerHide ledger
- [1]Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis Clin Microbiol Rev, 2010.PMID 20610819
- [2]Brouwer MC, Tunkel AR, van de Beek D. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis Lancet, 2012.PMID 23141617
- [3]Perry JJ, Sivilotti MLA, Émond M, et al. Validation of the Ottawa Subarachnoid Hemorrhage Rule in patients with acute headache CMAJ, 2017.PMID 29133539
- [4]Perry JJ, Wells JS, Sivilotti MLA, et al. Prospective Implementation of the Ottawa Subarachnoid Hemorrhage Rule and 6-Hour Computed Tomography Rule Stroke, 2020.PMID 31805846
- [5]Bezov D, Lipton RB, Ashina S, Ashina M. Post-dural puncture headache: part I diagnosis, epidemiology, etiology, and pathophysiology Headache, 2010.PMID 20533959
- [6]Bezov D, Ashina S, Lipton R, Ashina M. Post-dural puncture headache: Part II--prevention, management, and prognosis Headache, 2010.PMID 20807248
- [7]Arevalo-Rodriguez I, Muñoz L, Godoy-Casasbuenas N, et al. Needle gauge and tip designs for preventing post-dural puncture headache (PDPH) Cochrane Database Syst Rev, 2017.PMID 28388808
- [8]Rochwerg B, Almenawer SA, Siemieniuk RAC, et al. Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline BMJ, 2018.PMID 29789372
- [9]Gottlieb M, Holladay D, Peksa GD. Ultrasound-assisted Lumbar Punctures: A Systematic Review and Meta-Analysis Acad Emerg Med, 2019.PMID 30129102