Anaes Vivas · TIVA & target-controlled infusion
Effect-site TIVA — clinical and data viva
A data viva on the integrated TCI-pump and depth-monitor display: interpreting a rising depth index (real lightening versus artefact and paradoxical excitation), the plasma-versus-effect-site concept, and the principles of titrating a propofol-remifentanil TIVA.
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Prompt
You are shown a screen from a TCI pump running effect-site propofol and remifentanil, alongside a processed-EEG depth trace. The depth index has risen from 45 to 78 over two minutes with no change in surgery. Interpret the display and explain your response.
Stimulus
You are shown a screen from a TCI pump running effect-site propofol and remifentanil, alongside a processed-EEG depth trace. The depth index has risen from 45 to 78 over two minutes with no change in surgery. Interpret the display and explain your response.[2][3]
References3ShowHide
- [1]Felippe VA, et al. Closed-loop systems for automated hypnotic drug delivery during general anaesthesia: a systematic review and meta-analysis. Br J Anaesth, 2026.PMID 42014224
- [2]Sahinovic MM, Struys MMRF, et al. Clinical Pharmacokinetics and Pharmacodynamics of Propofol. Clin Pharmacokinet, 2018.PMID 30019172
- [3]Newman D, et al. Reframing "paradoxical" excitation: disentangling electroencephalogram complexity and entropy reveals resting-state dynamics associated with propofol susceptibility in healthy adults. Br J Anaesth, 2026.PMID 42225443