Anaes Vivas · TIVA & target-controlled infusion
Data viva — predicted vs measured concentration
A data viva on predicted vs actual — model prediction not measurement; individual variability; titrate to BIS not number; obesity and age adjust.
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Study tools
Target exams
ANZCAFRCAABAEDAIC
Prompt
A TCI display showing predicted propofol effect-site at 3.5 mcg/mL but BIS at 62 (above the 40-60 target). Interpret.
Stimulus
TCI display shows predicted propofol effect-site concentration 3.5 mcg/mL (target). But BIS reads 62 (above the 40-60 target). Patient not moving but heart rate rising. Interpret.
[1]References2ShowHide
- [1]Keresztes M, et al. Target-Controlled Infusion for Caesarean Delivery Under General Anesthesia: From Conventional Pharmacokinetic Models to Physiologically Based Pharmacokinetic Modeling. Life, 2026.PMID 42195295
- [4]Taplin CF, et al. Real-time propofol monitoring. Anaesth Intensive Care, 2026.PMID 42290030