Anaes Vivas · Applied cardiovascular & respiratory physiology
Data viva — cerebral autoregulation
A Primary data viva — read the cerebral autoregulation plateau; explain the right shift in chronic hypertension and its perioperative implication; explain CO2 reactivity and the use (and risk) of hyperventilation.
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Prompt
A graph shows cerebral blood flow (Y) against cerebral perfusion pressure (X), with a flat plateau from about 50 to 150 mmHg and a second dashed curve shifted to the right. Explain autoregulation, the effect of chronic hypertension, and the effect of changing PaCO2.
Stimulus
A graph shows cerebral blood flow on the Y-axis against cerebral perfusion pressure on the X-axis, with a flat plateau from about 50 to 150 mmHg and a second dashed curve shifted to the right. Explain autoregulation, the effect of chronic hypertension, and the effect of changing PaCO2.
References3ShowHide
- [1]Soule Z, et al. Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices. J Stroke, 2026.PMID 42237618
- [2]Ainslie PN, Duffin J. Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation. Am J Physiol Regul Integr Comp Physiol, 2009.PMID 19211719
- [3]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.