Anaes SAQs · Applied cardiovascular & respiratory physiology

Oxygen delivery and the Fick principle

Primary physiology — DO2 = CO x CaO2; the CaO2 = (1.34 x Hb x SaO2) + (0.003 x PaO2); the dominance of the bound haemoglobin; the 25 per cent resting extraction; the critical DO2 threshold; and the Fick principle (VO2 = CO x (CaO2 - CvO2)).