Anaes SAQs · Opioids & analgesics
The opioid-induced respiratory depression
Primary — the central chemoreflex (CO2 response) and the peripheral chemoreflex (hypoxic response) blunting; the dose-dependent; the synergistic with sedatives; the naloxone reversal (the titrated); the monitoring.
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Prompt
Describe the mechanism, the clinical features, and the management of the opioid-induced respiratory depression.
Question
Describe the mechanism, the clinical features, and the management of the opioid-induced respiratory depression.
[4]References2ShowHide
- [3]Lewis T, et al. Acute fentanyl toxicity: from opioid-induced to hypoxia-mediated pathophysiology. J Neurophysiol, 2026.PMID 42333655
- [4]Peng YJ, et al. Opioid-induced respiratory depression: peripheral chemoreflex. J Neurophysiol, 2026.PMID 42166777