Anaes SAQs · Opioids & analgesics
The opioid receptor pharmacology and the agents
Primary — the mu/kappa/delta receptors; the fentanyl (rapid, lipid-soluble), remifentanil (ultra-short, esterase metabolism), morphine (long-acting, M6G metabolite), alfentanil, sufentanil; the context-sensitive half-time.
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Target exams
ANZCAFRCAABAEDAIC
Prompt
Describe the opioid receptor pharmacology and match the common perioperative opioid agents to their receptor profile, pharmacokinetics, and clinical use.
Question
Describe the opioid receptor pharmacology and match the common perioperative opioid agents to their receptor profile, pharmacokinetics, and clinical use.
References2ShowHide
- [1]Ayazbekova A, et al. Role of Opioid-Free Anesthesia Versus Opioid-Based Anesthesia in Postoperative Pain and Opioid Consumption: A Systematic Review and Meta-Analysis. J Clin Med, 2026.PMID 42355728
- [42355729]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.