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Anaes SAQsLocal anaesthetic systemic toxicity

Anaes SAQs · Local anaesthetic systemic toxicity

The LAST — the presentation and the prevention

Primary — the early CNS signs (the circumoral tingling, the metallic taste, the agitation); the late (the seizure, the cardiac arrest); the prevention (the ultrasound, the aspiration, the fractionation, the dose limits, the patient factors).

10 marks10 min1 min readVerification in progress

Target exams

ANZCAFRCAABAEDAIC
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Target exams

ANZCAFRCAABAEDAIC
Prompt
Describe the clinical presentation of the LAST and the measures to prevent it.

Question

Describe the clinical presentation of the LAST and the measures to prevent it.

Anaesthesia Pro

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You have read the opening of this SAQ. The complete unit — every section and its primary-source references — is part of the Anaesthesia fellowship library.

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References3ShowHide
  1. [1]Pham DT, et al. New long-acting local anesthetics: safety. Curr Opin Anaesthesiol, 2026.PMID 42228505
  2. [3]Uysal AI, et al. Local anesthesia: safety and limitations. Aesthet Plast Surg, 2026.PMID 41559381
  3. [42228506]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
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