Anaes SAQs · Applied cardiovascular & respiratory physiology

Applied physiology of the elderly

Primary — cardiovascular (vessel stiffness, beta-sensitivity, baroreflex); respiratory (compliance, hypoxic drive 50 percent less, PPC risk); renal (GFR 1 mL per min per year, creatinine underestimates); hepatic (blood flow and Phase I slower); CNS (MAC 6 percent per decade, POCD); PK (more fat, less albumin, slower clearance); frailty stronger than age; delirium prevention.