Psych Vivas · Psychopharmacology — lithium
Lithium — consultant viva
Fellowship viva covering lithium efficacy, TDM, organ monitoring, interactions, pregnancy, toxicity and EXTRIP.
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Study tools
Target exams
FRANZCPMRCPsychABPNMD-DNB
Prompt
Examiner places cards: BALANCE, Cipriani suicide meta, 12-hour trough, NSAID start, McKnight organs, pregnancy first trimester, EXTRIP, older adult lower target.
Station structure
Time: 8–10 minutes. Depth: consultant teaching registrar. Expect named trials, 12-hour trough discipline, organ monitoring (not levels alone), interaction ladder, modern pregnancy absolute-risk framing, and EXTRIP language without inventing one hospital's exact mmol/L as universal law beyond published EXTRIP thresholds.[1][2][6][7]
References8ShowHide
- [1]Geddes JR, Goodwin GM, Rendell J, et al. Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial Lancet, 2010.PMID 20092882
- [2]Cipriani A, Hawton K, Stockton S, et al. Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis BMJ, 2013.PMID 23814104
- [3]McKnight RF, Adida M, Budge K, et al. Lithium toxicity profile: a systematic review and meta-analysis Lancet, 2012.PMID 22265699
- [4]Patorno E, Huybrechts KF, Bateman BT, et al. Lithium Use in Pregnancy and the Risk of Cardiac Malformations N Engl J Med, 2017.PMID 28591541
- [5]Munk-Olsen T, Liu X, Viktorin A, et al. Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies Lancet Psychiatry, 2018.PMID 29929874
- [6]Decker BS, Goldfarb DS, Dargan PI, et al. Extracorporeal Treatment for Lithium Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup Clin J Am Soc Nephrol, 2015.PMID 25583292
- [7]Hiemke C, Bergemann N, Clement HW, et al. Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017 Pharmacopsychiatry, 2018.PMID 29390205
- [8]Gitlin M Lithium side effects and toxicity: prevalence and management strategies Int J Bipolar Disord, 2016.PMID 27900734