Psych Vivas · Addiction psychiatry
Benzodiazepine dependence — structured clinical viva
Fellowship viva on BZD/Z-drug dependence in older adults, deprescribing, taper safety, and interaction hazards.
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Reveal interpretationShowHide
Reject the junior plan. Abrupt stop after 12 years risks severe withdrawal including seizures. Flumazenil is not community detox. Zolpidem/zopiclone are not safe long-term elderly substitutes — they act at related GABA-A sites and carry falls/cognition risk. Vitamins alone are not a taper.[3][1][6]
Elderly harm frame. Falls, fractures, cognitive adverse events, delirium risk; Glass meta-analysis shows modest sleep benefit versus harm; Markota review summarises dangers and alternatives.[1][2]
Plan. Shared deprescribing: education (EMPOWER logic), Canadian BRZA-style conversation, convert/combine to a single taperable regimen, gradual reductions, CBT-I/sleep hygiene, review polypharmacy, involve daughter as support not as enforcer of cold turkey, monitor mobility and cognition.[4][5][7][3]
Interactions. Counsel against alcohol and future opioid co-use because of synergistic depression.[6]
References7ShowHide
- [1]Markota M, Rummans TA, Bostwick JM, et al. Benzodiazepine Use in Older Adults: Dangers, Management, and Alternative Therapies Mayo Clin Proc, 2016.PMID 27814838
- [2]Glass J, Lanctôt KL, Herrmann N, et al. Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits BMJ, 2005.PMID 16284208
- [3]Brett J, Murnion B. Management of benzodiazepine misuse and dependence Aust Prescr, 2015.PMID 26648651
- [4]Tannenbaum C, Martin P, Tamblyn R, et al. Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial JAMA Intern Med, 2014.PMID 24733354
- [5]Pottie K, Thompson W, Davies S, et al. Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline Can Fam Physician, 2018.PMID 29760253
- [6]Soyka M. Treatment of Benzodiazepine Dependence N Engl J Med, 2017.PMID 28614686
- [7]Brunner E, Chen CA, Klein T, et al. Joint Clinical Practice Guideline on Benzodiazepine Tapering: Considerations When Risks Outweigh Benefits J Gen Intern Med, 2025.PMID 40526204