Mentalisation-based treatment

Meet the patient

A 28-year-old receptionist is in front of you for the third time this year. Her boyfriend of six weeks paused for two seconds before replying to a text, and in the six hours since she has cut her forearm, sent forty-seven messages, and drunk half a bottle of vodka. She is certain — absolutely certain — he is about to leave her. "I know what he's thinking. He hates me."[7][6]

Every registrar reaches for the crisis protocol. The examiner's question is narrower and harder: why is she so sure of his mind, and what treatment actually rebuilds her capacity to wonder? Everything below answers that.[5][7]

References18Show ledgerHide ledger

1. [1]Bateman A, Fonagy P Effectiveness of partial hospitalization in the treatment of borderline personality disorder: a randomized controlled trial Am J Psychiatry, 1999.PMID 10518167
2. [2]Bateman A, Fonagy P Treatment of borderline personality disorder with psychoanalytically oriented partial hospitalization: an 18-month follow-up Am J Psychiatry, 2001.PMID 11136631
3. [3]Bateman A, Fonagy P 8-year follow-up of patients treated for borderline personality disorder: mentalization-based treatment versus treatment as usual Am J Psychiatry, 2008.PMID 18347003
4. [4]Bateman A, Fonagy P Randomized controlled trial of outpatient mentalization-based treatment versus structured clinical management for borderline personality disorder Am J Psychiatry, 2009.PMID 19833787
5. [5]Fonagy P, Bateman AW Mechanisms of change in mentalization-based treatment of BPD J Clin Psychol, 2006.PMID 16470710
6. [6]Bateman A, Fonagy P Mentalization based treatment for borderline personality disorder World Psychiatry, 2010.PMID 20148147
7. [7]Fonagy P, Luyten P A developmental, mentalization-based approach to the understanding and treatment of borderline personality disorder Dev Psychopathol, 2009.PMID 19825272
8. [8]Rossouw TI, Fonagy P Mentalization-based treatment for self-harm in adolescents: a randomized controlled trial J Am Acad Child Adolesc Psychiatry, 2012.PMID 23200287
9. [9]Bateman A, O'Connell J, Lorenzini N, et al. A randomised controlled trial of mentalization-based treatment versus structured clinical management for patients with comorbid borderline personality disorder and antisocial personality disorder BMC Psychiatry, 2016.PMID 27577562
10. [10]Bateman A, Fonagy P A randomized controlled trial of a mentalization-based intervention (MBT-FACTS) for families of people with borderline personality disorder Personal Disord, 2019.PMID 29999394
11. [11]Cristea IA, Gentili C, Cotet CD, et al. Efficacy of Psychotherapies for Borderline Personality Disorder: A Systematic Review and Meta-analysis JAMA Psychiatry, 2017.PMID 28249086
12. [12]Storebø OJ, Stoffers-Winterling JM, Völlm BA, et al. Psychological therapies for people with borderline personality disorder Cochrane Database Syst Rev, 2020.PMID 32368793
13. [13]Stoffers-Winterling JM, Storebø OJ, Kongerslev MT, et al. Psychotherapies for borderline personality disorder: a focused systematic review and meta-analysis Br J Psychiatry, 2022.PMID 35088687
14. [14]Barnicot K, Crawford M Dialectical behaviour therapy v. mentalisation-based therapy for borderline personality disorder Psychol Med, 2019.PMID 30303061
15. [15]McMain SF, Links PS, Gnam WH, et al. A randomized trial of dialectical behavior therapy versus general psychiatric management for borderline personality disorder Am J Psychiatry, 2009.PMID 19755574
16. [16]Giesen-Bloo J, van Dyck R, Spinhoven P, et al. Outpatient psychotherapy for borderline personality disorder: randomized trial of schema-focused therapy vs transference-focused psychotherapy Arch Gen Psychiatry, 2006.PMID 16754838
17. [17]Bateman A, Campbell C, Luyten P, et al. A mentalization-based approach to common factors in the treatment of borderline personality disorder Curr Opin Psychol, 2018.PMID 28985628
18. [18]Fonagy P, Simes E, Yirmiya K, et al. Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial with economic evaluation Lancet Psychiatry, 2025.PMID 39978982