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Phys Topicsgeriatric

Phys · geriatric

Falls and Syncope in Older Adults

Also known as falls in older adults · syncope · transient loss of consciousness · vasovagal syncope · carotid sinus hypersensitivity · carotid sinus syndrome · orthostatic hypotension · postural hypotension · drop attack · multifactorial falls · Timed Up and Go test · Otago exercise programme

Consultant-physician-depth guide to falls and syncope in older adults for FRACP DWE and DCE — epidemiology, the multifactorial risk-factor model, the focused assessment (gait, orthostatic BP, cognitive and cardiovascular), the evidence-graded multifactorial intervention bundle (Otago, tai chi, STOPP/START, home safety, pacemaker for cardioinhibitory carotid sinus hypersensitivity), and the ESC 2018 syncope classification (reflex, orthostatic, cardiac; and the TLOC mimics — seizure, hypoglycaemia, drop attack).

high11 referencesUpdated 26 July 202613 min readVerification in progress

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FRACP DWEFRACP DCEMRCP Part 1MRCP Part 2MRCP PACESABIM Internal Medicine

Red flags

  • Syncope on exertion or while supine — assume a cardiac cause until proven otherwise; investigate with ECG, echocardiography, and ambulatory monitoring, and admit for risk stratification (ESC 2018 high-risk features, PMID 29562304)
  • Palpitations preceding syncope, syncope with chest pain or dyspnoea, a family history of sudden death at a young age, or an abnormal ECG (bifascicular block, long QT, Brugada pattern, prior infarct, LVH) — these are the red-flag features of life-threatening arrhythmic syncope
  • A systolic murmur in a patient with syncope — think aortic stenosis or hypertrophic cardiomyopathy; echocardiography is mandatory before discharge
  • Unexplained syncope or falls in a patient with bifascicular block on ECG (right bundle branch block with left anterior or posterior fascicular block, or left bundle branch block) — the risk of progression to complete heart block is high and pacing is indicated if syncope is unexplained
  • Carotid sinus massage producing asystole greater than 3 seconds or a systolic drop greater than 50 mmHg in a patient with recurrent unexplained syncope — this is cardioinhibitory or vasodepressor carotid sinus syndrome and may warrant permanent pacing
  • A fall in an anticoagulated older patient with any impact to the head — a subdural haematoma can present subtly over hours to days; a normal GCS does not exclude it, and CT head is indicated if on anticoagulant, if reduced GCS, repeated vomiting, focal neurology, or age over 65 with head impact
  • Syncope followed by confusion, tongue-biting, incontinence, or a slow recovery — the diagnosis is seizure, not syncope, and the work-up is different
  • Orthostatic hypotension in a patient on multiple antihypertensives or psychotropics — the cause is the drugs, and the treatment is deprescribing, not adding fludrocortisone
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Target exams

FRACP DWEFRACP DCEMRCP Part 1MRCP Part 2MRCP PACESABIM Internal Medicine

Red flags

  • Syncope on exertion or while supine — assume a cardiac cause until proven otherwise; investigate with ECG, echocardiography, and ambulatory monitoring, and admit for risk stratification (ESC 2018 high-risk features, PMID 29562304)
  • Palpitations preceding syncope, syncope with chest pain or dyspnoea, a family history of sudden death at a young age, or an abnormal ECG (bifascicular block, long QT, Brugada pattern, prior infarct, LVH) — these are the red-flag features of life-threatening arrhythmic syncope
  • A systolic murmur in a patient with syncope — think aortic stenosis or hypertrophic cardiomyopathy; echocardiography is mandatory before discharge
  • Unexplained syncope or falls in a patient with bifascicular block on ECG (right bundle branch block with left anterior or posterior fascicular block, or left bundle branch block) — the risk of progression to complete heart block is high and pacing is indicated if syncope is unexplained
  • Carotid sinus massage producing asystole greater than 3 seconds or a systolic drop greater than 50 mmHg in a patient with recurrent unexplained syncope — this is cardioinhibitory or vasodepressor carotid sinus syndrome and may warrant permanent pacing
  • A fall in an anticoagulated older patient with any impact to the head — a subdural haematoma can present subtly over hours to days; a normal GCS does not exclude it, and CT head is indicated if on anticoagulant, if reduced GCS, repeated vomiting, focal neurology, or age over 65 with head impact
  • Syncope followed by confusion, tongue-biting, incontinence, or a slow recovery — the diagnosis is seizure, not syncope, and the work-up is different
  • Orthostatic hypotension in a patient on multiple antihypertensives or psychotropics — the cause is the drugs, and the treatment is deprescribing, not adding fludrocortisone

Falls and Syncope in Older Adults

The answer first

A fall is an unintentional loss of balance ending on the ground or a lower level. Syncope is a transient loss of consciousness from global cerebral hypoperfusion — rapid onset, short duration, spontaneous complete recovery. The two overlap in older adults: many who have syncope present with an unexplained fall and no recall of losing consciousness, because there was no witness. Your job is threefold — separate syncope from its mimics, find the cause by history and examination rather than by ordering every test, and address the multifactorial risk profile.[1]

Falls are the leading cause of injury death in adults over 65, and syncope is the cause that kills — cardiac syncope carries a one-year mortality of 20 to 30 percent and must not be missed. The good news is that the largest part of the problem, multifactorial falls in community-dwelling older adults, is preventable and treatable: exercise programmes reduce the fall rate by about 23 percent.[3]

The classic trap: the initial evaluation of syncope is history, examination including orthostatic blood pressure, and a 12-lead ECG — and that triad alone yields the diagnosis in 60 to 70 percent of cases. Do not reflexively order a panel of CT head, carotid Dopplers, EEG, and Holter on every patient.[1]

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References11ShowHide
  1. [1]Brignole M, Moya A, de Lange FJ, et al. 2018 ESC Guidelines for the diagnosis and management of syncope Eur Heart J, 2018.PMID 29562304
  2. [2]Panel on Prevention of Falls in Older Persons, American Geriatrics Society and British Geriatrics Society Summary of the Updated American Geriatrics Society/British Geriatrics Society clinical practice guideline for prevention of falls in older persons J Am Geriatr Soc, 2011.PMID 21226685
  3. [3]Sherrington C, Fairhall NJ, Wallbank GK, et al. Exercise for preventing falls in older people living in the community Cochrane Database Syst Rev, 2019.PMID 30703272
  4. [4]Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community Cochrane Database Syst Rev, 2012.PMID 22972103
  5. [5]Campbell AJ, Robertson MC, Gardner MM, Norton RN, Tilyard MW, Buchner DM Randomised controlled trial of a general practice programme of home based exercise to prevent falls in elderly women BMJ, 1997.PMID 9366737
  6. [6]Campbell AJ, Robertson MC, Gardner MM, Norton RN, Buchner DM Falls prevention over 2 years: a randomized controlled trial in women 80 years and older Age Ageing, 1999.PMID 10604501
  7. [7]Lomas-Vega R, Obrero-Gaitán E, Molina-Ortega FJ, et al. Tai Chi for Risk of Falls. A Meta-analysis J Am Geriatr Soc, 2017.PMID 28736853
  8. [8]Grossman DC, Curry SJ, Owens DK, et al. Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement JAMA, 2018.PMID 29710141
  9. [9]O'Mahony D, O'Sullivan D, Byrne S, O'Connor MN, Ryan C, Gallagher P STOPP/START criteria for potentially inappropriate prescribing in older people: version 2 Age Ageing, 2015.PMID 25324330
  10. [10]Podsiadlo D, Richardson S The timed Up & Go: a test of basic functional mobility for frail elderly persons J Am Geriatr Soc, 1991.PMID 1991946
  11. [11]Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome Clin Auton Res, 2011.PMID 21431947

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