Phys · gastrointestinal
Functional GI Disorders
Also known as Functional GI Disorders · functional gi disorders
Consultant-physician guide to disorders of gut-brain interaction for FRACP DWE and DCE: Rome IV irritable bowel syndrome and functional dyspepsia, alarm features, the minimum work-up, and first-line, second-line and psychological therapy from the BSG guidelines.
Checked against its sources on 23 Oct 2026
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FRACP DWEFRACP DCEMRCP Part 2ABIM Internal Medicine
Red flags
- Unexplained weight loss with abdominal pain at age 40 or over, or unexplained rectal bleeding at age 50 or over — BSG referral criteria for suspected colorectal cancer
- Persistent bloating or distension in a woman — consider CA-125 and pelvic ultrasound to exclude ovarian cancer
- Dyspepsia with weight loss at age 55 or over — urgent endoscopy
- Severe or refractory symptoms — review the diagnosis and avoid opioids and unnecessary surgery
The answer first
References7ShowHide
- [1]Vasant DH, Paine PA, Black CJ, et al. British Society of Gastroenterology guidelines on the management of irritable bowel syndrome. Gut, 2021.PMID 33903147
- [2]Black CJ, Paine PA, Agrawal A, et al. British Society of Gastroenterology guidelines on the management of functional dyspepsia. Gut, 2022.PMID 35798375
- [3]Lacy BE, Patel NK Rome Criteria and a Diagnostic Approach to Irritable Bowel Syndrome. Journal of clinical medicine, 2017.PMID 29072609
- [4]Black CJ, Staudacher HM, Ford AC Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis. Gut, 2022.PMID 34376515
- [5]Bertin L, Zanconato M, Crepaldi M, et al. The Role of the FODMAP Diet in IBS. Nutrients, 2024.PMID 38337655
- [6]Huang KY, Wang FY, Lv M, et al. Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment. World journal of gastroenterology, 2023.PMID 37475846
- [7]Aziz I, Whitehead WE, Palsson OS, et al. An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation. Expert review of gastroenterology & hepatology, 2020.PMID 31893959