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Phys Clinical Casesrenal

Phys Clinical Cases · renal

Nephrolithiasis — DCE Clinical Case

DCE long-case and short-case clinical station for nephrolithiasis: comprehensive assessment of a 48-year-old man with Crohn disease and recurrent calcium oxalate stones from enteric hyperoxaluria, with chronic diarrhoea, hypocitraturia, and a counterproductive low-calcium diet. Covers the pathophysiology of enteric hyperoxaluria, the metabolic evaluation, the acute management of renal colic, the prevention strategy (normal calcium with meals, potassium citrate, low-oxalate low-fat diet), and the emergency of obstructive pyelonephritis. Plus branching discussions on primary hyperparathyroidism, struvite staghorn calculus, and the SUSPEND trial evidence for medical expulsive therapy.

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DCE long-case and short-case clinical station for nephrolithiasis: comprehensive assessment of a 48-year-old man with Crohn disease and recurrent calcium oxalate stones from enteric hyperoxaluria, with chronic diarrhoea, hypocitraturia, and a counterproductive low-calcium diet. Covers the pathophysiology of enteric hyperoxaluria, the metabolic evaluation, the acute management of renal colic, the prevention strategy (normal calcium with meals, potassium citrate, low-oxalate low-fat diet), and the emergency of obstructive pyelonephritis. Plus branching discussions on primary hyperparathyroidism, struvite staghorn calculus, and the SUSPEND trial evidence for medical expulsive therapy.

Nephrolithiasis — DCE Clinical Case

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References7ShowHide
  1. [1]Moe OW Kidney stones: pathophysiology and medical management Lancet, 2006.PMID 16443041
  2. [2]Borghi L, Schianchi T, Meschi T, et al. Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria N Engl J Med, 2002.PMID 11784873
  3. [3]Smith-Bindman R, Aubin C, Bailitz J, et al. Ultrasonography versus computed tomography for suspected nephrolithiasis N Engl J Med, 2014.PMID 25229916
  4. [4]Pickard R, Starr K, MacLennan G, et al. Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial Lancet, 2015.PMID 25998582
  5. [5]Fink HA, Wilt TJ, Eidman KE, et al. Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians Clinical Guideline Ann Intern Med, 2013.PMID 23546565
  6. [6]Hollingsworth JM, Canales BK, Rogers MA, et al. Alpha blockers for treatment of ureteric stones: systematic review and meta-analysis BMJ, 2016.PMID 27908918
  7. [7]Curhan GC Epidemiology of stone disease Urol Clin North Am, 2007.PMID 17678980
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