Kidney Transplantation — Clinical Case

DCE long case for kidney transplantation: a 52-year-old man with diabetic kidney disease, six months post deceased-donor kidney transplant, presenting with a rising creatinine and BK viraemia. Full patient assessment, SASPOP opening, structured problem list, integrated management plan (immunosuppression reduction, exclusion of concurrent rejection, cardiovascular risk modification, lifelong surveillance), and probing examiner questions.

Prompt

Kidney Transplantation — Clinical Case

References8Show

[1]Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant N Engl J Med, 1999.PMID 10580071
[2]Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D Improved graft survival after renal transplantation in the United States, 1988 to 1996 N Engl J Med, 2000.PMID 10699159
[3]Chadban SJ, Ahn C, Axelrod DA, et al. KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation Transplantation, 2020.PMID 32301874
[4]Ekberg H, Tedesco-Silva H, Demirbas A, et al. Reduced exposure to calcineurin inhibitors in renal transplantation N Engl J Med, 2007.PMID 18094377
[5]Solez K, Colvin RB, Racusen LC, et al. Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN') Am J Transplant, 2007.PMID 17352710
[6]Kotton CN, Kumar D, Caliendo AM, et al. The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation Transplantation, 2018.PMID 29596116
[7]Kotton CN, Kamar N, Wojciechowski D, et al. The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation Transplantation, 2024.PMID 38605438
[8]Taylor AL, Marcus R, Bradley JA Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation Crit Rev Oncol Hematol, 2005.PMID 15979320

References8Show

[1]Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant N Engl J Med, 1999.PMID 10580071
[2]Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D Improved graft survival after renal transplantation in the United States, 1988 to 1996 N Engl J Med, 2000.PMID 10699159
[3]Chadban SJ, Ahn C, Axelrod DA, et al. KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation Transplantation, 2020.PMID 32301874
[4]Ekberg H, Tedesco-Silva H, Demirbas A, et al. Reduced exposure to calcineurin inhibitors in renal transplantation N Engl J Med, 2007.PMID 18094377
[5]Solez K, Colvin RB, Racusen LC, et al. Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN') Am J Transplant, 2007.PMID 17352710
[6]Kotton CN, Kumar D, Caliendo AM, et al. The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation Transplantation, 2018.PMID 29596116
[7]Kotton CN, Kamar N, Wojciechowski D, et al. The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation Transplantation, 2024.PMID 38605438
[8]Taylor AL, Marcus R, Bradley JA Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation Crit Rev Oncol Hematol, 2005.PMID 15979320