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Healthcare-Associated Infections — DCE Clinical Case
DCE long-case clinical station: comprehensive assessment of a 68-year-old man who is day 7 post-emergency laparotomy for perforated sigmoid diverticulum and develops Pseudomonas aeruginosa catheter-related bloodstream infection and concurrent ventilator-associated pneumonia — covering the diagnostic strategy (paired blood cultures and differential time to positivity), the management of both foci, the central line and ventilator prevention bundles, the stewardship review of the preceding broad-spectrum antibiotic exposure, and the long-term prevention and quality improvement plan — structured for FRACP DCE and MRCP PACES.
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Healthcare-Associated Infections — Clinical Case
You have read the opening of this clinical case. The complete unit — every section and its primary-source references — is part of the Physician Medicine fellowship atlas.
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- [1]Pronovost P, Needham D, Berenholtz S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU N Engl J Med, 2006.PMID 17192537
- [2]O'Grady NP, Alexander M, Burns LA, et al. Guidelines for the prevention of intravascular catheter-related infections Clin Infect Dis, 2011.PMID 21460264
- [3]Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America Clin Infect Dis, 2009.PMID 19489710
- [4]Martinez-Reviejo R, Tejada S, Jansson M, et al. Prevention of ventilator-associated pneumonia through care bundles: A systematic review and meta-analysis J Intensive Med, 2023.PMID 38028633
- [5]Muscedere J, Rewa O, McKechnie K, et al. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis Crit Care Med, 2011.PMID 21478738
- [6]McDonald LC, Gerding DN, Johnson S, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) Clin Infect Dis, 2018.PMID 29462280