Phys Clinical Cases · infectious
Fungal Infections — DCE Clinical Case
DCE long-case clinical station: comprehensive assessment of a 34-year-old man with HIV (CD4 24) who presents with a 3-week history of progressive headache, photophobia, and confusion, diagnosed with cryptococcal meningitis with an opening pressure of 38 cm of water — covering the three-phase antifungal regimen, the single most important principle of raised intracranial pressure management with serial therapeutic lumbar punctures, the timing of antiretroviral therapy and the IRIS risk, the AMBITION and ACTA evidence, and the long-term consolidation, maintenance, and prophylaxis plan — structured for FRACP DCE and MRCP PACES.
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DCE long-case clinical station: comprehensive assessment of a 34-year-old man with HIV (CD4 24) who presents with a 3-week history of progressive headache, photophobia, and confusion, diagnosed with cryptococcal meningitis with an opening pressure of 38 cm of water — covering the three-phase antifungal regimen, the single most important principle of raised intracranial pressure management with serial therapeutic lumbar punctures, the timing of antiretroviral therapy and the IRIS risk, the AMBITION and ACTA evidence, and the long-term consolidation, maintenance, and prophylaxis plan — structured for FRACP DCE and MRCP PACES.
Fungal Infections — Clinical Case
References3ShowHide
- [1]Perfect JR, Dismukes WE, Dromer F, et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america Clin Infect Dis, 2010.PMID 20047480
- [2]Jarvis JN, Lawrence DS, Meya DB, et al. Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis N Engl J Med, 2022.PMID 35320642
- [3]Molloy SF, Kanyama C, Heyderman RS, et al. Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa N Engl J Med, 2018.PMID 29539274