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Phys Clinical Caseshepatic

Phys Clinical Cases · hepatic

Autoimmune Liver Disease — Clinical Case

DCE long case for autoimmune liver disease: a 54-year-old woman with an AIH-PBC overlap syndrome presenting with fatigue, pruritus and jaundice. Full patient assessment, SASPOP opening, structured problem list, integrated management plan (UDCA for the PBC component, prednisolone plus azathioprine after TPMT check for the AIH component, cirrhosis surveillance, pruritus and bone health management, transplant assessment), and probing examiner questions.

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FRACP DCEMRCP PACES
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FRACP DCEMRCP PACES
Prompt
DCE long case for autoimmune liver disease: a 54-year-old woman with an AIH-PBC overlap syndrome presenting with fatigue, pruritus and jaundice. Full patient assessment, SASPOP opening, structured problem list, integrated management plan (UDCA for the PBC component, prednisolone plus azathioprine after TPMT check for the AIH component, cirrhosis surveillance, pruritus and bone health management, transplant assessment), and probing examiner questions.

Autoimmune Liver Disease — Clinical Case

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References7ShowHide
  1. [1]Kaplan MM, Gershwin ME Primary biliary cirrhosis N Engl J Med, 2005.PMID 16177252
  2. [2]Poupon RE, Poupon R, Balkau B Ursodiol for the long-term treatment of primary biliary cirrhosis. The UDCA-PBC Study Group N Engl J Med, 1994.PMID 8152446
  3. [3]Nevens F, Andreone P, Mazzella G, et al. A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis N Engl J Med, 2016.PMID 27532829
  4. [4]Hirschfield GM, Karlsen TH, Lindor KD, Adams DH Primary sclerosing cholangitis Lancet, 2013.PMID 23810223
  5. [5]Manns MP, Czaja AJ, Gorham JD, et al. Diagnosis and management of autoimmune hepatitis Hepatology, 2010.PMID 20513004
  6. [6]Hennes EM, Zeniya M, Czaja AJ, et al. Simplified criteria for the diagnosis of autoimmune hepatitis Hepatology, 2008.PMID 18537184
  7. [7]Boberg KM, Chapman RW, Hirschfield GM, et al. Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue J Hepatol, 2011.PMID 21067838
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