Poisoning antidotes and toxicology pharmacology — branching viva

My first moves are ABCDE resuscitation before any antidote. I would secure and protect his airway, support his breathing with bag-valve-mask ventilation because his respiratory rate of eight is inadequate, establish intravenous access, and give a fluid bolus if he is shocked. I would check a bedside glucose immediately because hypoglycaemia mimics poisoning and is instantly reversible. His pin-point pupils and slow breathing are an opioid toxidrome, so I would give naloxone 10 microgram per kilogram intravenously — about 160 microgram — repeated every two to three minutes, titrated to his respiratory rate. I would also take a focused history of what and how much was taken and when, and call the regional poison information centre. ^{[3] [4]}