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Paeds Vivaspaediatric-dermatology

Paeds Vivas · paediatric-dermatology

Petechiae, purpura and vasculitic rashes — branching viva

Branching structured-oral viva on petechiae, purpura and vasculitic rashes in children: the sick-versus-well first split and the glass test, the emergency pathway for meningococcaemia and purpura fulminans, the ISTH disseminated intravascular coagulation score, the definition of immune thrombocytopenia and its differentiation from leukaemia, the EULAR/PRINTO/PRES criteria and renal monitoring for IgA vasculitis, and the TEN-4 FACES safeguarding assessment of bruising.

branching clinical structured oral5 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
You are the general paediatric registrar in the emergency department. A 14-month-old is brought with fever, irritability and a spreading petechial rash that is becoming dark and purpuric, with cool peripheries and a four-second capillary refill. The examiner asks you to take the candidate through the triage, the emergency management, the differential of a non-blanching rash, the definition and differentiation of immune thrombocytopenia, and the safeguarding assessment of bruising.

Opening question

Examiner: Take me through this child. What is your immediate frame? [8]

Candidate: This is a sick child with a rapidly progressive non-blanching rash and signs of septic shock — meningococcal septicaemia or purpura fulminans until proven otherwise. My first split is sick versus well, and this child is unwell: the fever, irritability, cool peripheries, prolonged capillary refill and the spreading dark purpuric rash all place her in the emergency pathway. My immediate frame is the first-hour sepsis bundle: oxygen, access, blood cultures, a broad-spectrum parenteral antibiotic such as ceftriaxone, and a fluid bolus, with escalation to intensive care. [8] [9]

Examiner: How do you confirm the rash is non-blanching? [8]

Candidate: With the glass test. I press a clear glass or transparent tumbler firmly over a lesion; petechiae and purpura remain visible through the glass because the blood is extravascular, whereas an erythematous inflammatory rash would fade. A non-blanching rash means blood outside the vessel lumen, which points me to a platelet, vessel-wall or coagulation problem. [8]

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References7ShowHide
  1. [1]Provan D; Arnold DM; Bussel JB; et al Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv, 2019.PMID 31770441
  2. [3]Rodeghiero F; Stasi R; Gernsheimer T; et al Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood, 2009.PMID 19005182
  3. [4]Grace RF; Lambert MP; et al An update on pediatric ITP: differentiating primary ITP, IPD, and PID. Blood, 2022.PMID 34479363
  4. [5]Ozen S; Pistorio A; Iusan SM; et al EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis, 2010.PMID 20413568
  5. [8]Sabra A; Benger J Meningococcal disease in children: a clinical review. Turk J Pediatr, 2011.PMID 22272447
  6. [9]Taylor FB Jr; Toh CH; Hoots WK; et al Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost, 2001.PMID 11816725
  7. [12]Pierce MC; Kaczor K; Aldridge S; et al Bruising characteristics discriminating physical child abuse from accidental trauma. Pediatrics, 2010.PMID 19969620
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