Paeds Vivas · respiratory-sleep-and-airway
Asthma diagnosis and long-term control — branching viva
Branching viva from the definition and objective confirmation of childhood asthma through the phenotype and control classification, the inflammatory pathophysiology, the stepwise controller ladder and the anti-inflammatory reliever evidence, to the poorly controlled adolescent and the diagnostic mimics.
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Target exams
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Prompt
You are the paediatric registrar in a respiratory clinic. The consultant asks you to talk through four children: a 7-year-old with recurrent cough and wheeze needing a diagnosis, a preschooler with recurrent viral wheeze, an adolescent whose asthma looks uncontrolled, and a child whose 'asthma' has never responded to treatment.
Station opening
Examiner: "Define asthma in a child and explain why it is a clinical diagnosis rather than one made on a single test." [5]
Strong candidate (must-hit)
- Defines asthma as a chronic inflammatory disorder of the airways producing variable, reversible airflow obstruction, presenting as recurrent, trigger-provoked, nocturnal wheeze, cough, breathlessness and chest tightness that respond to a bronchodilator; explains that there is no single confirmatory test, so the diagnosis rests on the characteristic variable pattern, the objective demonstration of variable airflow limitation, and the exclusion of the mimics; and names variability and reversibility as the two defining features. [5] [10]
Weak candidate
- "Asthma is when a child wheezes and we give them a blue inhaler." [5]
References6ShowHide
- [1]Martinez FD; Wright AL; Taussig LM; Holberg CJ; Halonen M; Morgan WJ Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med, 1995.PMID 7800004
- [2]Castro-Rodríguez JA; Holberg CJ; Wright AL; Martinez FD A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med, 2000.PMID 11029352
- [5]Bacharier LB; Boner A; Carlsen KH; Eigenmann PA; Frischer T; Götz M; et al Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy, 2008.PMID 18053013
- [8]O'Byrne PM; FitzGerald JM; Bateman ED; Barnes PJ; Zhong N; Keen C; et al Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma. N Engl J Med, 2018.PMID 29768149
- [10]Levy ML; Bacharier LB; Bateman E; Boulet LP; Brightling C; Buhl R; et al Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update. NPJ Prim Care Respir Med, 2023.PMID 36754956
- [11]Chauhan BF; Ducharme FM Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev, 2012.PMID 22592685