Paeds · paediatric-dermatology
Scabies, lice and infestations
Also known as scabies · Sarcoptes scabiei · crusted scabies · Norwegian scabies · head lice · pediculosis capitis · pubic lice · phthiriasis · body lice · ectoparasite infestation
Human ectoparasite infestations of childhood — scabies (Sarcoptes scabiei), head lice (Pediculus humanus capitis), pubic lice and body lice — presenting with characteristic itchy burrows or nits, diagnosed clinically using the 2020 IACS criteria, and managed with permethrin or ivermectin while treating all household contacts on the same day.
On this page & tools
Your progress
Saved locally on this device.
Practise this topic
Target exams
Red flags
Life stages
Care settings
Clinical exam formats
Board mappings
Overview & Definition
A school-age child who cannot sleep because of an itch that burns worst at night, with burrows in the finger-webs and a sibling scratching just as badly, is the everyday face of scabies. Human ectoparasite infestations are infections of the skin by arthropods that have adapted to live on people: the scabies mite burrows into the stratum corneum, while lice cling to hair or clothing and feed on blood. Scabies alone affects more than 200 million people at any time, and in remote and overcrowded communities it is one of the commonest reasons a child presents to a clinician. [2]
The clinical thread that unites scabies and pediculosis is itch, but the mechanism differs. Scabies itch is a delayed allergy to mite antigens that takes weeks to develop, which is why a first infestation is silent at first and overwhelming by the time it is recognised. Louse itch is an immediate reaction to bites and saliva, together with the local damage caused by scratching. Both are contagious, both invite secondary bacterial infection, and both demand treatment of the child together with every household and close contact on the same day. [3]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship atlas.
References11Show ledgerHide ledger
- [1]Engelman D, Fuller LC, Steer AC The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies. Br J Dermatol, 2020.PMID 32034956
- [2]Karimkhani C, Colombara DV, Drucker AM The global burden of scabies: a cross-sectional analysis from the Global Burden of Disease Study 2015. Lancet Infect Dis, 2017.PMID 28941561
- [3]Currie BJ, McCarthy JS Permethrin and ivermectin for scabies. N Engl J Med, 2010.PMID 20181973
- [4]Dhana A, Yen H, Okhovat JP, et al. Ivermectin versus permethrin in the treatment of scabies: A systematic review and meta-analysis of randomized controlled trials. J Am Acad Dermatol, 2018.PMID 29241784
- [5]Romani L, Whitfeld MJ, Koroivueta J Mass Drug Administration for Scabies Control in a Population with Endemic Disease. N Engl J Med, 2015.PMID 26650152
- [6]Aung PTZ, Cuningham W, Hwang K Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study. PLoS Negl Trop Dis, 2018.PMID 30044780
- [7]Mounsey KE, Holt DC, McCarthy J Scabies: molecular perspectives and therapeutic implications in the face of emerging drug resistance. Future Microbiol, 2008.PMID 18230034
- [8]Meinking TL, Villar ME, Vicaria M The clinical trials supporting benzyl alcohol lotion 5% (Ulesfia): a safe and effective topical treatment for head lice (pediculosis humanus capitis). Pediatr Dermatol, 2010.PMID 20199404
- [9]Deeks LS, Naunton M, Currie MJ, et al. Topical ivermectin 0.5% lotion for treatment of head lice. Ann Pharmacother, 2013.PMID 24259731
- [10]Heukelbach J, Pilger D, Oliveira FA, et al. A highly efficacious pediculicide based on dimeticone: randomized observer blinded comparative trial. BMC Infect Dis, 2008.PMID 18783606
- [11]Cole SW, Lundquist LM Spinosad for treatment of head lice infestation. Ann Pharmacother, 2011.PMID 21750308