Paeds · nephrology-urology-fluids-and-electrolytes
Dehydration and oral or intravenous rehydration
Also known as Paediatric dehydration · Acute gastroenteritis dehydration · Oral rehydration therapy · Intravenous rehydration in children · Clinical dehydration scale
Fellowship guide to paediatric dehydration and rehydration: the clinical dehydration scale and the WHO and percentage-weight-loss severity bands, the assessment of volume status at the bedside, oral rehydration therapy with reduced-osmolarity oral rehydration solution as the first-line treatment for mild to moderate dehydration, the staged intravenous rehydration protocol with isotonic crystalloid and the slow correction of dysnatraemia, and the prevention of cerebral oedema that dominates the safe management of the severely dehydrated child.
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Overview & Definition
A child who has been vomiting and passing watery stools for two days, who is now listless with sunken eyes and a dry mouth, is the everyday face of dehydration and the most common paediatric fluid emergency. The defining problem is a net loss of body water and electrolytes that outruns intake, so the extracellular volume contracts and the circulating volume falls until the tissues are underperfused. Most episodes follow acute gastroenteritis, and most are mild, but the small proportion that progress to severe dehydration carry a real risk of shock, electrolyte crisis, and cerebral oedema. [11]
The degree of dehydration is expressed most usefully as a percentage of body weight lost, because a recent weight is the single most reliable measure of the water deficit. A loss below 5 percent of body weight is mild and usually clinically inapparent, a loss of 5 to 10 percent produces the recognisable signs of moderate dehydration, and a loss above 10 percent is severe and accompanied by shock and a threatened circulation. The clinical dehydration scale converts these weight bands into a reproducible bedside score, so the clinician can grade severity without waiting for a weight or a blood test. [4]
The treatment is simple in concept and exact in execution, which is the whole point of the topic for an examiner. Mild and moderate dehydration are managed with oral rehydration therapy using reduced-osmolarity oral rehydration solution, which works as well as intravenous fluid and avoids the cannula and the admission. Severe dehydration and shock need intravenous isotonic crystalloid in a staged protocol, and the dysnatraemic child needs that fluid given slowly, because the brain defends its volume and a rapid correction causes cerebral oedema. [7]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship atlas.
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- [1]Holliday MA, Segar WE The maintenance need for water in parenteral fluid therapy. Pediatrics, 1957.PMID 13431307
- [2]Steiner MJ, DeWalt DA, Byerley JS Is this child dehydrated? JAMA, 2004.PMID 15187057
- [3]Gorelick MH, Shaw KN, Murphy KO Validity and reliability of clinical signs in the diagnosis of dehydration in children. Pediatrics, 1997.PMID 9113963
- [4]Friedman JN, Goldman RD, Srivastava R, Parkin PC Development of a clinical dehydration scale for use in children between 1 and 36 months of age. J Pediatr, 2004.PMID 15289767
- [5]Goldman RD, Friedman JN, Parkin PC Validation of the clinical dehydration scale for children with acute gastroenteritis. Pediatrics, 2008.PMID 18762524
- [6]Freedman SB, Willan AR, Boutis K, Schuh S Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis: A Randomized Clinical Trial. JAMA, 2016.PMID 27131100
- [7]Hartling L, Bellemare S, Wiebe N, Russell K, et al Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children. Cochrane Database Syst Rev, 2006.PMID 16856044
- [8]Freedman SB, Adler M, Seshadri R, Powell EC Oral ondansetron for gastroenteritis in a pediatric emergency department. N Engl J Med, 2006.PMID 16625009
- [9]Duggan C, Fontaine O, Pierce NF, Glass RI, et al Scientific rationale for a change in the composition of oral rehydration solution. JAMA, 2004.PMID 15173155
- [10]Neilson J, O'Neill F, Dawoud D, Crean P, et al Intravenous fluids in children and young people: summary of NICE guidance. BMJ, 2015.PMID 26662119
- [11]Khanna R, Lakhanpaul M, Burman-Roy S, Murphy MS, et al Diarrhoea and vomiting caused by gastroenteritis in children under 5 years: summary of NICE guidance. BMJ, 2009.PMID 19386673
- [12]Ozdogan T, Iscan M, Ellikcioglu C, Yildiz E Hypernatraemic dehydration in breast-fed neonates. Arch Dis Child, 2006.PMID 17119086