Paeds · investigations-procedures-and-technology
Neuroimaging selection and radiation-aware practice
Also known as Neuroimaging in children · CT versus MRI · PECARN head injury rule · Paediatric radiation safety · ALARA in children · Image Gently
Fellowship guide to choosing between CT, MRI, cranial ultrasound and skull radiograph in infants and children, and to the radiation-aware principles that govern that choice. Covers why CT uses ionising radiation and MRI does not, why the paediatric brain carries a measurably higher lifetime attributable cancer risk per millisievert with the Brenner, Pearce and Meulepas cohort estimates, the ALARA principle and its four levers, the PECARN paediatric head injury prediction rules reproduced verbatim for the under-two and two-and-over arms, the indications for urgent neuroimaging in seizures, stroke, shunt malfunction, raised intracranial pressure and suspected abusive head trauma, the MRI safety issues in children including sedation and gadolinium, the regional guideline differences (NICE, PECARN, Canadian, RCH Melbourne, RCPCH), and how to counsel a parent accurately about the absolute and relative radiation risk of a single head CT.
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Overview & Definition
Picture the toddler who has just fallen from a shopping trolley, crying but alert, or the seven-year-old sent up from the general practitioner with a first-ever afebrile seizure overnight. In both, the team faces the same question: does this child need a picture of the brain, and if so, which picture. That question is the territory this page owns — not the brain itself, but the choice between the modalities that image it, and the radiation-aware reasoning that keeps the child safe while the question is answered. [10] [12]
Neuroimaging is the production of an image of the brain, its coverings, its vessels and the surrounding skull and cerebrospinal-fluid spaces. In modern paediatric practice the four modalities in routine use are computed tomography (CT), magnetic resonance imaging (MRI), cranial ultrasound, and the skull radiograph. Each answers a different question, each carries a different trade-off between speed, cooperation, diagnostic yield and — crucially for the child — radiation dose. The fellowship skill being tested is reading the clinical question, choosing the modality that answers it at the lowest harm, and defending that choice with the evidence. [10] [12]
The reason radiation-aware practice is a distinct skill in children is that children are not small adults when it comes to ionising radiation. A given effective dose delivered to a child carries a measurably higher lifetime attributable cancer risk than the same dose delivered to an adult, both because the child has more rapidly dividing tissue and because the child has many more decades over which a radiation-induced malignancy can emerge. The cohorts that established this — Brenner's risk model, the UK CT-in-childhood study of Pearce, and the Dutch cohort of Meulepas — changed practice: they did not forbid CT, but they made every paediatric CT a deliberate, justified, dose-optimised decision. [2] [3] [4]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship atlas.
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- [1]Kuppermann N, Holmes JF, Dayan PS, et al Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study Lancet, 2009.PMID 19758692
- [2]Brenner D, Elliston C, Hall E, Berdon W Estimated risks of radiation-induced fatal cancer from pediatric CT AJR Am J Roentgenol, 2001.PMID 11159059
- [3]Pearce MS, Salotti JA, Little MP, et al Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study Lancet, 2012.PMID 22681860
- [4]Meulepas JM, Ronckers CM, Smets AMJB, et al Radiation Exposure From Pediatric CT Scans and Subsequent Cancer Risk in the Netherlands J Natl Cancer Inst, 2019.PMID 30020493
- [5]Hirtz D, Ashwal S, Berg A, et al Practice parameter: evaluating a first nonfebrile seizure in children Neurology, 2000.PMID 10980722
- [6]Shinnar S, O'Dell C, Mitnick R, Berg AT, Moshe SL Neuroimaging abnormalities in children with an apparent first unprovoked seizure Epilepsy Res, 2001.PMID 11248538
- [7]Subcommittee on Febrile Seizures, American Academy of Pediatrics Neurodiagnostic evaluation of the child with a simple febrile seizure Pediatrics, 2011.PMID 21285335
- [8]Wilne S, Koller K, Collier J, Kennedy C, Grundy R, Walker D The diagnosis of brain tumours in children: a guideline to assist healthcare professionals in the assessment of children who may have a brain tumour Arch Dis Child, 2010.PMID 20371594
- [9]Wilmshurst JM, Gaillard WD, Vinayan KP, et al Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics Epilepsia, 2015.PMID 26122601
- [10]Frush DP, Frush KS The ALARA concept in pediatric imaging: building bridges between radiology and emergency medicine Pediatr Radiol, 2008.PMID 18810422
- [11]Mirsky DM, Beslow LA, Amlie-Lefond C, et al Pathways for Neuroimaging of Childhood Stroke Pediatr Neurol, 2017.PMID 28274641
- [12]Goske MJ, Strauss KJ, Westra SJ, Frush DP The Image Gently ALARA CT summit on new CT technologies for children Pediatr Radiol, 2014.PMID 25304694