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Paeds Topicsfetal-neonatal-and-perinatal

Paeds · fetal-neonatal-and-perinatal

Newborn examination and screening

Also known as Routine newborn check · Newborn infant physical examination · First newborn examination · NIPE · Newborn screening examination · 6-week baby check

Fellowship-level systematic newborn examination and universal newborn screening: head-to-toe assessment within 24-72 hours, the four targeted screens (pulse oximetry for critical congenital heart disease, red reflex for cataract and retinoblastoma, hearing screen, hip examination), New Ballard Score for gestational age, benign transitional findings versus pathology, escalation of abnormal findings, and ANZ/UK/US/Canada programme differences.

high20 referencesUpdated 11 July 202617 min readVerification in progress

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Target exams

RACP General PaediatricsRACP DWERACP DCERCPCH Progress+MRCPCH TheoryMRCPCH ClinicalABP General PediatricsACGME PediatricsRCPSC Pediatrics

Red flags

  • White pupil (leucocoria) on red reflex — retinoblastoma or congenital cataract until proven otherwise; same-day ophthalmology
  • Differential or low oxygen saturations on pulse oximetry screen — duct-dependent congenital heart disease before collapse
  • Bilious vomiting — malrotation with volvulus until proven otherwise; nil-by-mouth and urgent surgical referral
  • Jaundice within the first 24 hours — always pathological; measure bilirubin and investigate haemolysis
  • Absent femoral pulses or weak upper-limb pulses — coarctation or interrupted aortic arch
  • Midline spinal skin lesion with a dimple above the gluteal cleft, hair tuft, or lipoma — occult spinal dysraphism
  • Poor feeding, lethargy, or temperature instability — neonatal sepsis until excluded

Life stages

neonate

Care settings

delivery-roomnicuwardoutpatientpreventive-medical-home

Clinical exam formats

written-onlyracp-dce-short-casemrcpch-short-clinicalrcpsc-structured-oral

Board mappings

  • Neonatology — newborn examination and screening
  • General and Community Paediatrics
  • Learning goal: essential general paediatrics — newborn assessment
  • Learning goal: recognition and management of congenital anomalies and the dysmorphic newborn
  • Neonatology — newborn examination and routine screening
  • Clinical Applications — interpretation of newborn screening tests
  • Short Cases — newborn examination
  • Long Cases — congenital anomalies and the dysmorphic newborn
  • 1. Frameworks for clinical practice — newborn assessment
  • 8. Lead and collaborate within teams — abnormal screening results and referral
  • Foundation of Practice (FOP) — newborn examination
  • Applied Knowledge in Practice (AKP) — newborn screening
  • History
  • Examination — newborn and infant
  • Communication — explaining screening results
  • General Pediatrics Content Outline — Domain 3: Fetus and Newborn Infant
  • General Pediatrics Content Outline — Universal Task 5: Prevention
  • Patient Care 1: Screening and Preventive Services
  • Patient Care 5: Patient Management
  • Medical Knowledge 1: Neonatology and newborn care
  • Medical Expert — newborn examination
  • Communicator — conveying screening results to families
  • Pediatrics: Foundations EPA #3 — Perform a complete history and physical examination
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  • Short-answer question1
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Target exams

RACP General PaediatricsRACP DWERACP DCERCPCH Progress+MRCPCH TheoryMRCPCH ClinicalABP General PediatricsACGME PediatricsRCPSC Pediatrics

Red flags

  • White pupil (leucocoria) on red reflex — retinoblastoma or congenital cataract until proven otherwise; same-day ophthalmology
  • Differential or low oxygen saturations on pulse oximetry screen — duct-dependent congenital heart disease before collapse
  • Bilious vomiting — malrotation with volvulus until proven otherwise; nil-by-mouth and urgent surgical referral
  • Jaundice within the first 24 hours — always pathological; measure bilirubin and investigate haemolysis
  • Absent femoral pulses or weak upper-limb pulses — coarctation or interrupted aortic arch
  • Midline spinal skin lesion with a dimple above the gluteal cleft, hair tuft, or lipoma — occult spinal dysraphism
  • Poor feeding, lethargy, or temperature instability — neonatal sepsis until excluded

Life stages

neonate

Care settings

delivery-roomnicuwardoutpatientpreventive-medical-home

Clinical exam formats

written-onlyracp-dce-short-casemrcpch-short-clinicalrcpsc-structured-oral

Board mappings

  • Neonatology — newborn examination and screening
  • General and Community Paediatrics
  • Learning goal: essential general paediatrics — newborn assessment
  • Learning goal: recognition and management of congenital anomalies and the dysmorphic newborn
  • Neonatology — newborn examination and routine screening
  • Clinical Applications — interpretation of newborn screening tests
  • Short Cases — newborn examination
  • Long Cases — congenital anomalies and the dysmorphic newborn
  • 1. Frameworks for clinical practice — newborn assessment
  • 8. Lead and collaborate within teams — abnormal screening results and referral
  • Foundation of Practice (FOP) — newborn examination
  • Applied Knowledge in Practice (AKP) — newborn screening
  • History
  • Examination — newborn and infant
  • Communication — explaining screening results
  • General Pediatrics Content Outline — Domain 3: Fetus and Newborn Infant
  • General Pediatrics Content Outline — Universal Task 5: Prevention
  • Patient Care 1: Screening and Preventive Services
  • Patient Care 5: Patient Management
  • Medical Knowledge 1: Neonatology and newborn care
  • Medical Expert — newborn examination
  • Communicator — conveying screening results to families
  • Pediatrics: Foundations EPA #3 — Perform a complete history and physical examination
The fellowship answer

The newborn examination is a systematic, head-to-toe assessment performed within 24-72 hours of birth whose real job is to find the serious conditions that are otherwise silent in a well-looking baby. Four targeted universal screens do most of the heavy lifting: pulse oximetry for critical congenital heart disease, the red reflex for cataract and retinoblastoma, the hearing screen for congenital hearing loss, and the hip examination for developmental dysplasia. Know the benign transitional findings so you do not over-investigate them, and know the red flags so you escalate the same day. Examine warm, with the parent present, hips last, and document everything. [1] [11]

Overview & Definition

A registrar is asked to "check the baby" before discharge. The parents are tired and anxious. This is one of the highest-yield examinations in paediatrics, because the serious findings — a duct-dependent heart, a cataract, a dislocatable hip — are easy to miss in a baby who looks completely well. [1]

The newborn examination (also called the routine infant check, the newborn infant physical examination, or NIPE in the UK) is a structured head-to-toe assessment carried out within the first 24 to 72 hours of life, before discharge home. It combines a full physical examination with the targeted universal screening tests. [19]

Two ideas sit behind it. First, a small number of conditions are treatable if found early and devastating if missed — the screening exists because they are silent at first. Second, most findings in a newborn are benign and transitional, so an important part of the job is recognising normal variants and reassuring parents well. [1]

The timing that matters

The examination is best performed after the baby has stabilised from birth, typically between 24 and 72 hours of age. Examining too early underestimates findings (cardiac lesions emerge as the duct closes; jaundice rises after 24 hours). Examining before discharge closes the window where the silent conditions declare themselves. [1]

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References20ShowHide
  1. [1]Mahle WT Role of pulse oximetry in examining newborns for congenital heart disease: a scientific statement from the AHA and AAP. Pediatrics, 2009.PMID 19581259
  2. [2]Plana MN Pulse oximetry screening for critical congenital heart defects. The Cochrane database of systematic reviews, 2018.PMID 29494750
  3. [3]Kemper AR Strategies for implementing screening for critical congenital heart disease. Pediatrics, 2011.PMID 21987707
  4. [4]Ballard JL New Ballard Score, expanded to include extremely premature infants. The Journal of pediatrics, 1991.PMID 1880657
  5. [5]Zhang S Developmental dysplasia of the hip. British journal of hospital medicine (London, England : 2005), 2020.PMID 32730146
  6. [6]Maikku M The Ortolani test has a high positive predictive value in clinical hip screening for developmental dysplasia of the hip. Acta paediatrica (Oslo, Norway : 1992), 2023.PMID 36928888
  7. [7]Kolovos S Ultrasonographic screening for developmental dysplasia of the hip: the Graf method revisited. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2024.PMID 37884843
  8. [8]Wrightson AS Universal newborn hearing screening. American family physician, 2007.PMID 17508530
  9. [9]Wroblewska-Seniuk KE Universal newborn hearing screening: methods and results, obstacles, and benefits. Pediatric research, 2017.PMID 27861465
  10. [10]Thompson DC Universal newborn hearing screening: summary of evidence. JAMA, 2001.PMID 11667937
  11. [11]Cagini C Red reflex examination in neonates: evaluation of 3 years of screening. International ophthalmology, 2017.PMID 27822637
  12. [12]Duret A The infrared reflex: a potential new method for congenital cataract screening. Eye (London, England), 2019.PMID 31267092
  13. [13]Bruney TL Systematic review of the evidence for resolution of common breastfeeding problems-Ankyloglossia (Tongue Tie). Acta paediatrica (Oslo, Norway : 1992), 2022.PMID 35150472
  14. [14]O'Shea JE Frenotomy for tongue-tie in newborn infants. The Cochrane database of systematic reviews, 2017.PMID 28284020
  15. [15]Kucera JN The simple sacral dimple: diagnostic yield of ultrasound in neonates. Pediatric radiology, 2015.PMID 24996813
  16. [16]Albert GW Spine ultrasounds should not be routinely performed for patients with simple sacral dimples. Acta paediatrica (Oslo, Norway : 1992), 2016.PMID 27059606
  17. [17]Jullien S Vitamin K prophylaxis in newborns. BMC pediatrics, 2021.PMID 34496783
  18. [18]Sankar MJ Vitamin K prophylaxis for prevention of vitamin K deficiency bleeding: a systematic review. Journal of perinatology : official journal of the California Perinatal Association, 2016.PMID 27109090
  19. [19]Townsend J Routine examination of the newborn: the EMREN study. Evaluation of an extension of the midwife role including a randomised controlled trial of appropriately trained midwives and paediatric senior house officers. Health technology assessment (Winchester, England), 2004.PMID 15038906
  20. [20]Par EJ Neonatal Hyperbilirubinemia: Evaluation and Treatment. American family physician, 2023.PMID 37192079

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