Skip to main content
MedVellum
QuestionsVideosPricing

MedVellum

Fellowship exam preparation across every specialty: source-verified topics, questions in every format, and videos.

Product

  • Specialties
  • Questions
  • Videos
  • Exam tools
  • Pricing

Verification & policy

  • Verified register
  • Editorial policy
  • Privacy
  • Terms

Account

  • Sign in
  • Create account
  • Dashboard
  • Account & billing

© 2026 MedVellum. For education only — not a substitute for clinical judgement.

llms.txtPsychiatry LLM catalogSitemap

Paeds Topicscardiology

Paeds · cardiology

Heart failure in infants and children

Also known as Heart failure in infants and children · Paediatric heart failure · Congestive heart failure in children · Infant heart failure · Cardiomyopathy with heart failure

Fellowship guide to heart failure as a clinical syndrome in infants and children: the volume-overload, pressure-overload and pump-failure mechanisms, the modified Ross severity grading, the neurohormonal vicious cycle, the infant presentation of tachypnoea and failure to thrive, echocardiographic assessment, acute resuscitation and chronic neurohormonal therapy, the carvedilol evidence, and escalation to the Berlin Heart EXCOR ventricular assist device and transplantation.

high12 referencesUpdated 13 July 202624 min readVerification in progress

Practise this topic

  • SAQ
  • Viva
  • Case

Your progress

Saved on this device.

Practise this topic

  • Short-answer question1
  • Viva station1
  • Clinical case1

Target exams

RACP DWERACP DCEMRCPCH TheoryMRCPCH Clinical

Red flags

  • An infant who becomes increasingly breathless, sweats with feeds and crosses weight centiles downward at four to eight weeks is in pulmonary overcirculation from a left-to-right shunt as the pulmonary vascular resistance falls — assess urgently with echocardiography and start heart-failure therapy
  • A previously well child with a viral prodrome who develops tachypnoea, a gallop rhythm and hepatomegaly has acute myocarditis until proven otherwise — this can deteriorate rapidly to cardiogenic shock and needs urgent echocardiography, troponin and a low threshold for intensive care
  • A duct-dependent lesion (hypoplastic left heart, critical aortic stenosis, interrupted aortic arch, severe coarctation) collapses when the ductus closes in the first days of life with shock and poor perfusion rather than congestion — start prostaglandin E1 immediately while arranging echocardiography
  • Giving indiscriminate high-flow oxygen to an infant with a large left-to-right shunt lowers pulmonary vascular resistance, increases the shunt and can worsen overcirculation failure — titrate oxygen to saturations

Life stages

fetalneonateinfanttoddlerpreschoolschool-ageadolescentyoung-adult-transition

Care settings

preventive-medical-homeoutpatientwarded-acutenicupicuretrievalrural-remote

Clinical exam formats

written-only

Board mappings

  • Heart failure in infants and children
  • Heart failure in infants and children: mechanism, modified Ross grading, and management
  • Heart failure in infants and children: recognition, acute management, and the carvedilol evidence
  • Short case: the infant with tachypnoea and failure to thrive
  • Long case: the child with a cardiomyopathy and heart-failure follow-up
  • Heart failure in infants and children: classification, pathophysiology, and management
  • Cardiac: the infant in heart failure
  • Cardiology: heart failure in infants and children
  • Patient Care: heart failure in infants and children
  • Medical Expert: heart failure in infants and children
On this page
Study tools

Your progress

Saved on this device.

Practise this topic

  • Short-answer question1
  • Viva station1
  • Clinical case1

Target exams

RACP DWERACP DCEMRCPCH TheoryMRCPCH Clinical

Red flags

  • An infant who becomes increasingly breathless, sweats with feeds and crosses weight centiles downward at four to eight weeks is in pulmonary overcirculation from a left-to-right shunt as the pulmonary vascular resistance falls — assess urgently with echocardiography and start heart-failure therapy
  • A previously well child with a viral prodrome who develops tachypnoea, a gallop rhythm and hepatomegaly has acute myocarditis until proven otherwise — this can deteriorate rapidly to cardiogenic shock and needs urgent echocardiography, troponin and a low threshold for intensive care
  • A duct-dependent lesion (hypoplastic left heart, critical aortic stenosis, interrupted aortic arch, severe coarctation) collapses when the ductus closes in the first days of life with shock and poor perfusion rather than congestion — start prostaglandin E1 immediately while arranging echocardiography
  • Giving indiscriminate high-flow oxygen to an infant with a large left-to-right shunt lowers pulmonary vascular resistance, increases the shunt and can worsen overcirculation failure — titrate oxygen to saturations

Life stages

fetalneonateinfanttoddlerpreschoolschool-ageadolescentyoung-adult-transition

Care settings

preventive-medical-homeoutpatientwarded-acutenicupicuretrievalrural-remote

Clinical exam formats

written-only

Board mappings

  • Heart failure in infants and children
  • Heart failure in infants and children: mechanism, modified Ross grading, and management
  • Heart failure in infants and children: recognition, acute management, and the carvedilol evidence
  • Short case: the infant with tachypnoea and failure to thrive
  • Long case: the child with a cardiomyopathy and heart-failure follow-up
  • Heart failure in infants and children: classification, pathophysiology, and management
  • Cardiac: the infant in heart failure
  • Cardiology: heart failure in infants and children
  • Patient Care: heart failure in infants and children
  • Medical Expert: heart failure in infants and children

Overview & Definition

Heart failure in a child is a clinical syndrome in which the heart cannot deliver enough blood to meet the body's metabolic demands, or can do so only at abnormally high filling pressures. It is not a single diagnosis: it is the end result of many different problems, and the whole skill of paediatric heart failure lies in finding the mechanism that is failing. [3]

Because cardiac output is the product of stroke volume and heart rate, anything that reduces stroke volume — a failing pump, a volume load that dilates the ventricle, or a pressure load that stiffens it — produces the same syndrome of poor perfusion and congestion. In adults heart failure is usually the consequence of coronary disease and a stiff, aging myocardium; in children it is usually the consequence of a structural congenital lesion or an intrinsic cardiomyopathy, which is why so much of childhood heart failure is surgically curable once the cause is found. [3] [4]

What is paediatric heart failure, and why is the mechanism more important than the label?

Heart failure in a child is the syndrome in which the heart cannot deliver adequate cardiac output or does so only at raised filling pressure. The mechanism decides everything that follows: a volume-overload shunt (VSD, PDA) dilates the left heart and is cured by closing the shunt; a pressure-load obstruction (coarctation, aortic stenosis) stiffens the ventricle and is cured by relieving the obstruction; an intrinsic pump failure (dilated cardiomyopathy, myocarditis) requires neurohormonal therapy and, if refractory, mechanical support and transplantation. Naming the mechanism, not the syndrome, is the task. [3] [6]

The four-to-eight-week presentation of overcirculation

A moderate-to-large left-to-right shunt is often silent at birth because the neonatal pulmonary vascular resistance is still high. As that resistance falls over the first six to eight weeks, the shunt increases and the infant develops tachypnoea, poor feeding, sweating with feeds and failure to thrive. Any infant presenting in this window with these signs needs urgent echocardiography and heart-failure therapy — the diagnosis is pulmonary overcirculation from the shunt, not a feeding problem. [1]

Paediatrics Fellowship Pro

Continue reading

You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship library.

Sign in to continueSee pricing
References12ShowHide
  1. [1]Hoffman JI; Kaplan S The incidence of congenital heart disease. J Am Coll Cardiol, 2002.PMID 12084585
  2. [2]van der Linde D; Konings EE; Slager MA; Witsenburg M; Helbing WA; Takkenberg JJ; Roos-Hesselink JW Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J Am Coll Cardiol, 2011.PMID 22078432
  3. [3]Hsu DT; Pearson GD Heart failure in children: part I: history, etiology, and pathophysiology. Circ Heart Fail, 2009.PMID 19808316
  4. [4]Hsu DT; Pearson GD Heart failure in children: part II: diagnosis, treatment, and future directions. Circ Heart Fail, 2009.PMID 19808380
  5. [5]Ross RD The Ross classification for heart failure in children after 25 years: a review and an age-stratified revision. Pediatr Cardiol, 2012.PMID 22476605
  6. [6]Kantor PF; Lougheed J; Dancea A; McGillion M; Barbosa N; Chan W; Cherney DZ; Gandhi S; Holtby HM; Human DG; McCrindle BW; Prieur T; Conway J; Canadian Cardiovascular Society Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines. Can J Cardiol, 2013.PMID 24267800
  7. [7]Shaddy RE; Boucek MM; Hsu DT; Boucek RJ; Sanders SP; Mineral S; Pahl E; Miyamoto SD; Tresed M; Pediatic Carvedilol Study Group Carvedilol for children and adolescents with heart failure: a randomized controlled trial. JAMA, 2007.PMID 17848651
  8. [8]Rossano JW; Kantor PF; Shaddy RE; Shi L; Lipshultz SE; Colan SD; Sleeper LA; Towbin JA; Jefferies JL; Everitt MD; Hsu DT; Wilkinson JD; Pediatric Cardiomyopathy Registry Elevated heart rate and survival in children with dilated cardiomyopathy: a multicenter study from the Pediatric Cardiomyopathy Registry. J Am Heart Assoc, 2020.PMID 32750307
  9. [9]Kantor PF; Shi L; Colan SD; Orav EJ; Mayer JE; Sleeper LA; Lipshultz SE; Pediatric Cardiomyopathy Registry Progressive left ventricular remodeling for predicting mortality in children with dilated cardiomyopathy: the Pediatric Cardiomyopathy Registry. J Am Heart Assoc, 2024.PMID 38214257
  10. [10]Almond CS; Morales DL; Blackstone EH; Turrentine MW; Imamura M; Massicotte MP; Jordan LC; Meyer DM; Das NA; Lorts A; Morales RS; Davies RR; Nikaidoh H; Muenzer JR; Rosenthal DN; Morell VO; Kanter KR; Mahle WT; Fraser CD Jr Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children. Circulation, 2013.PMID 23538380
  11. [11]Baumgartner H; De Backer J; Babu-Narayan SV; Budts W; Chessa M; Diller GP; Lung B; Kluin J; Lang IM; Meijboom F; Moons P; Mulder BJM; Oechslin E; Roos-Hesselink JW; Schwerzmann M; Sullebarger L; Van Hare GF; ESC Scientific Document Group 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J, 2020.PMID 33128054
  12. [12]Wilson WR; Gewitz M; Lockhart PB; Bolger AF; DeSimone DC; Koenig MJ; Sadhu Lohr J; Miro JM; Padera RF; Prendergast BD; Sexton DJ; Spelman DW; Tleyjeh IM; Van der Meer JTM; Westermann CJL; Whited W; Wojda TR; American Heart Association Prevention of Viridans Group Streptococcal Infective Endocarditis: A Scientific Statement From the American Heart Association. Circulation, 2021.PMID 33853363

Test yourself

Practise what you just read

  • SAQ
  • Viva
  • Case
Paediatrics Fellowship Pro

$29/ monthor $279 / year

The complete Paediatrics Fellowship library, every exam format, one subscription.

  • Complete library for one chosen specialty
  • Timed MCQ mock exams and spaced review
  • Clinical cases & cross-table vivas
See pricingSign in
PreviousExercise evaluation and sports participation in heart diseasecardiologyNextHypertension in childrencardiology