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Paeds Topicsacute-care-resuscitation-and-toxicology

Paeds · acute-care-resuscitation-and-toxicology

Humane restraint and behavioural support in emergency care

Also known as Acute behavioural disturbance in children · Paediatric agitation management · Rapid tranquillisation in children · De-escalation in the emergency department · Physical restraint of children · Chemical restraint in paediatric emergency care

A fellowship approach to the child or young person with acute behavioural disturbance in the emergency department. Run a primary survey and treat medical causes first, lead verbal de-escalation and environmental modification, offer oral medication with consent before any injection, escalate to parenteral rapid tranquillisation only when oral fails or is unsafe, reserve physical restraint for grave and imminent danger with minimum force and minimum duration by a trained team, monitor every sedated child for respiratory depression, QTc prolongation and oversedation, and debrief the child, family and team afterwards.

high12 referencesUpdated 17 July 202642 min readVerification in progress

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Target exams

RACP General PaediatricsRACP DWERACP DCERCPCH Progress+MRCPCH TheoryMRCPCH ClinicalABP General PediatricsACGME PediatricsRCPSC Pediatrics

Red flags

  • Agitation in a child with fever, abnormal observations, focal neurological signs, pupil changes, abnormal movements or fluctuating consciousness is medical or toxicological until proven otherwise
  • A bedside glucose must be checked in any agitated child with altered consciousness; hypoglycaemia is the most reversible and most missed cause
  • Combining intramuscular olanzapine with a parenteral benzodiazepine in the same visit risks severe respiratory depression, hypotension and airway loss; the FDA has warned against this combination without close monitoring
  • A child held face-down, in a hobble restraint, or with airway obstruction during restraint is at risk of positional asphyxia and sudden death; the airway must be visible and protected at all times
  • Droperidol and haloperidol prolong the QT interval; an ECG is required with cardiac history, electrolyte disturbance, other QT-prolonging drugs, methamphetamine intoxication or high cumulative doses
  • Antipsychotic-naive children have a high rate of extrapyramidal, sedation and metabolic adverse effects; start low, titrate, and monitor
  • A restrained child is a vulnerable child; an automatic safeguarding review is required for any child in care and for any unexplained or repeated restraint
  • Oversedation, rising respiratory rate falling, falling oxygen saturation or unable to maintain airway after sedation means call senior, PICU or retrieval now

Life stages

infanttoddlerpreschoolschool-ageadolescentyoung-adult-transition

Care settings

ed-acutewardpicuretrievalrural-remotetelehealth

Clinical exam formats

written-onlyracp-dce-long-caseracp-dce-short-casemrcpch-short-clinicalmrcpch-history-managementmrcpch-communicationmrcpch-videorcpsc-structured-oral

Board mappings

  • Acute Care
  • Behavioural and Mental Health
  • Current 2026 PREP curriculum — Learning Objective 2.2.1: Recognise, prioritise and manage an acutely ill infant, child or young person
  • Current 2026 PREP curriculum — Learning Objective 2.2.2: Perform comprehensive and accurate clinical assessments
  • Current 2026 PREP curriculum — Learning Objective 2.2.3: Perform acute resuscitation and advanced life support
  • Current 2026 PREP curriculum — Learning Objective 2.4.7: Assess and manage common behavioural, developmental and mental health presentations in infants, children and young people
  • Current 2026 PREP curriculum — Learning Objective 2.5.2: Practise with a commitment to child protection, advocacy and the United Nations Convention on the Rights of the Child
  • Renewed curriculum for first-year trainees from 2027 — Learning goal 11: Acute care and procedures
  • Renewed curriculum for first-year trainees from 2027 — Learning goal 17: Acute care
  • Clinical Applications
  • Medical Sciences
  • Ethics and Law
  • Long Cases
  • Short Cases
  • Communication
  • 3. Professional skills and knowledge: Clinical procedures
  • 4. Professional skills and knowledge: Patient management
  • 6. Leadership and team working
  • 7. Patient safety, including safe prescribing
  • 8. Safeguarding
  • 9. Equality, diversity and inclusion
  • Mental Health: Assesses and manages children and young people presenting with acute behavioural disturbance, self-harm or mental health crisis
  • Neurodisability: Manages acute behavioural disturbance in children with autism, intellectual disability or complex neurodisability
  • Foundation of Practice (FOP)
  • Theory and Science (TAS)
  • Applied Knowledge in Practice (AKP)
  • Clinical
  • History
  • Video
  • General Pediatrics Content Outline — Domain 7: Emergency and Critical Care
  • General Pediatrics Content Outline — Domain 10: Behavioural and Mental Health
  • General Pediatrics Content Outline — Universal Task 1: Physiology and Pathophysiology
  • General Pediatrics Content Outline — Universal Task 3: Diagnosis
  • General Pediatrics Content Outline — Universal Task 4: Management and Treatment
  • General Pediatrics Content Outline — Universal Task 6: Professional Conduct, Ethics, and Legal Principles
  • General Pediatrics EPA 7: Recognizing a Severely Ill Patient, Providing Initial Management, and Mobilizing Resources Needed for Continued Care
  • General Pediatrics EPA 12: Assessing and managing children and adolescents with behavioural and mental health concerns
  • Patient Care 3: Organize and Prioritize Patient Care
  • Patient Care 4: Clinical Reasoning
  • Patient Care 5: Patient Management
  • Interpersonal and Communication Skills 1: Patient and Family-Centered Communication
  • Interpersonal and Communication Skills 2: Interprofessional and Team Communication
  • Professionalism 3: Ethical Principles
  • Systems-Based Practice 1: Patient Safety
  • Medical Expert
  • Communicator
  • Collaborator
  • Health Advocate
  • Pediatrics: Foundations EPA #1 — Recognizing deteriorating and/or critically ill patients and initiating stabilization and management
  • Pediatrics: Core EPA #2 — Resuscitating and stabilizing critically ill patients
  • Pediatrics: Core EPA #9 — Assessing and managing children and youth with mental health and behavioural concerns
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Practise this topic

  • Short-answer question1
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Target exams

RACP General PaediatricsRACP DWERACP DCERCPCH Progress+MRCPCH TheoryMRCPCH ClinicalABP General PediatricsACGME PediatricsRCPSC Pediatrics

Red flags

  • Agitation in a child with fever, abnormal observations, focal neurological signs, pupil changes, abnormal movements or fluctuating consciousness is medical or toxicological until proven otherwise
  • A bedside glucose must be checked in any agitated child with altered consciousness; hypoglycaemia is the most reversible and most missed cause
  • Combining intramuscular olanzapine with a parenteral benzodiazepine in the same visit risks severe respiratory depression, hypotension and airway loss; the FDA has warned against this combination without close monitoring
  • A child held face-down, in a hobble restraint, or with airway obstruction during restraint is at risk of positional asphyxia and sudden death; the airway must be visible and protected at all times
  • Droperidol and haloperidol prolong the QT interval; an ECG is required with cardiac history, electrolyte disturbance, other QT-prolonging drugs, methamphetamine intoxication or high cumulative doses
  • Antipsychotic-naive children have a high rate of extrapyramidal, sedation and metabolic adverse effects; start low, titrate, and monitor
  • A restrained child is a vulnerable child; an automatic safeguarding review is required for any child in care and for any unexplained or repeated restraint
  • Oversedation, rising respiratory rate falling, falling oxygen saturation or unable to maintain airway after sedation means call senior, PICU or retrieval now

Life stages

infanttoddlerpreschoolschool-ageadolescentyoung-adult-transition

Care settings

ed-acutewardpicuretrievalrural-remotetelehealth

Clinical exam formats

written-onlyracp-dce-long-caseracp-dce-short-casemrcpch-short-clinicalmrcpch-history-managementmrcpch-communicationmrcpch-videorcpsc-structured-oral

Board mappings

  • Acute Care
  • Behavioural and Mental Health
  • Current 2026 PREP curriculum — Learning Objective 2.2.1: Recognise, prioritise and manage an acutely ill infant, child or young person
  • Current 2026 PREP curriculum — Learning Objective 2.2.2: Perform comprehensive and accurate clinical assessments
  • Current 2026 PREP curriculum — Learning Objective 2.2.3: Perform acute resuscitation and advanced life support
  • Current 2026 PREP curriculum — Learning Objective 2.4.7: Assess and manage common behavioural, developmental and mental health presentations in infants, children and young people
  • Current 2026 PREP curriculum — Learning Objective 2.5.2: Practise with a commitment to child protection, advocacy and the United Nations Convention on the Rights of the Child
  • Renewed curriculum for first-year trainees from 2027 — Learning goal 11: Acute care and procedures
  • Renewed curriculum for first-year trainees from 2027 — Learning goal 17: Acute care
  • Clinical Applications
  • Medical Sciences
  • Ethics and Law
  • Long Cases
  • Short Cases
  • Communication
  • 3. Professional skills and knowledge: Clinical procedures
  • 4. Professional skills and knowledge: Patient management
  • 6. Leadership and team working
  • 7. Patient safety, including safe prescribing
  • 8. Safeguarding
  • 9. Equality, diversity and inclusion
  • Mental Health: Assesses and manages children and young people presenting with acute behavioural disturbance, self-harm or mental health crisis
  • Neurodisability: Manages acute behavioural disturbance in children with autism, intellectual disability or complex neurodisability
  • Foundation of Practice (FOP)
  • Theory and Science (TAS)
  • Applied Knowledge in Practice (AKP)
  • Clinical
  • History
  • Video
  • General Pediatrics Content Outline — Domain 7: Emergency and Critical Care
  • General Pediatrics Content Outline — Domain 10: Behavioural and Mental Health
  • General Pediatrics Content Outline — Universal Task 1: Physiology and Pathophysiology
  • General Pediatrics Content Outline — Universal Task 3: Diagnosis
  • General Pediatrics Content Outline — Universal Task 4: Management and Treatment
  • General Pediatrics Content Outline — Universal Task 6: Professional Conduct, Ethics, and Legal Principles
  • General Pediatrics EPA 7: Recognizing a Severely Ill Patient, Providing Initial Management, and Mobilizing Resources Needed for Continued Care
  • General Pediatrics EPA 12: Assessing and managing children and adolescents with behavioural and mental health concerns
  • Patient Care 3: Organize and Prioritize Patient Care
  • Patient Care 4: Clinical Reasoning
  • Patient Care 5: Patient Management
  • Interpersonal and Communication Skills 1: Patient and Family-Centered Communication
  • Interpersonal and Communication Skills 2: Interprofessional and Team Communication
  • Professionalism 3: Ethical Principles
  • Systems-Based Practice 1: Patient Safety
  • Medical Expert
  • Communicator
  • Collaborator
  • Health Advocate
  • Pediatrics: Foundations EPA #1 — Recognizing deteriorating and/or critically ill patients and initiating stabilization and management
  • Pediatrics: Core EPA #2 — Resuscitating and stabilizing critically ill patients
  • Pediatrics: Core EPA #9 — Assessing and managing children and youth with mental health and behavioural concerns
The fellowship answer

Acute behavioural disturbance in a child is a behaviour with medical, psychiatric, toxicological and developmental drivers, never a diagnosis. Ensure the safety of the child, staff and others first, run a primary survey and treat the medical causes (hypoxia, hypoglycaemia, sepsis, pain, delirium) before any sedation, lead verbal de-escalation and environmental modification, offer oral medication with consent as the first pharmacological step, escalate to parenteral rapid tranquillisation only when oral fails or is unsafe, reserve physical restraint for grave and imminent danger with minimum force and minimum duration by a trained team, monitor every sedated child closely, debrief the child, family and team afterwards, and treat a restrained child as a vulnerable child with an automatic safeguarding lens. [1] [4]

Overview & Definition

Acute behavioural disturbance is what you see at the bedside before you know why: a child or young person whose behaviour has escalated to the point where they are a risk to themselves, to others, or to their own assessment and treatment. The presenting behaviour is pacing, shouting, threatening, throwing, self-harming, refusing, withdrawing, posturing or striking out. The job of the paediatric team in the emergency department is not to diagnose a psychiatric illness first; it is to keep everyone safe, find the drivers of the behaviour, settle the child by the least restrictive means that work, and only then hand on to mental health, paediatric, toxicology, developmental or safeguarding services as the cause demands. [1]

The defining frame is that acute behavioural disturbance is a behaviour, not a diagnosis. A wide range of medical, psychiatric, toxicological, developmental and situational drivers converge on the same final behaviour, and the differential is broadest at moment child arrives. This is why a calm, structured, least-restrictive approach that protects the brain and the airway while the cause is identified outperforms a reflex to sedate or restrain. [2] [3]

Agitation in a young child with no prior psychiatric history is medical until proven otherwise

The younger the child and shorter history, higher probability that a medical or toxicological cause is driving the agitation. New agitation in a child under twelve with no prior mental health history mandates exclusion of hypoxia, hypoglycaemia, sepsis, central nervous system infection, raised intracranial pressure, post-ictal state, toxidrome, pain and delirium before sedation. Treating agitation in this group with a sedative before excluding these causes is the classic pitfall, because the sedative masks the deteriorating medical child.

[1] [5]

The clinical and ethical anchor is the least-restrictive principle: the intervention that is sufficient to keep the child and others safe, and no more. Autonomy is the default; restriction is the exception, justified each time by imminent risk of serious harm, carried out with minimum force and minimum duration, and reviewed continuously. Restraint and sedation without consent are governed by mental health, guardianship and child-protection legislation, which varies across Australian states and territories, Aotearoa New Zealand, the United Kingdom and North America. Know the forms and thresholds that apply in your jurisdiction before you need them. [1] [2]

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References12ShowHide
  1. [1]Hilt RJ, Woodward TA Agitation treatment for pediatric emergency patients Journal of the American Academy of Child and Adolescent Psychiatry, 2008.PMID 18216715
  2. [2]TREC Collaborative Group Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine BMJ, 2003.PMID 14512476
  3. [3]Bourke EM, Borland ML, Kochar A, et al. Pharmacological emergency management of agitation in children and young people: protocol for a randomised controlled trial of oral medication (PEAChY-O) BMJ Open, 2023.PMID 36997250
  4. [4]Bourke EM, Kochar A, Shellshear D, et al. PEAChY-O: Pharmacological Emergency Management of Agitation in Children and Young People: A Randomized Controlled Trial of Oral Medication Annals of Emergency Medicine, 2025.PMID 39955661
  5. [5]Brasel K, LaScala E, Weeda E, et al. Pharmacotherapy for Agitation Management in a Pediatric Emergency Department Pediatric Emergency Care, 2025.PMID 39841042
  6. [6]Bourke EM, Say DF, Carison A, et al. Emergency mental health presentations in children with autism spectrum disorder and attention deficit hyperactivity disorder Journal of Paediatrics and Child Health, 2021.PMID 33963626
  7. [7]Malashock HR, Yeung C, Roberts AR, et al. Pediatric Methamphetamine Toxicity: Clinical Manifestations and Therapeutic Use of Antipsychotics-One Institution's Experience Journal of Medical Toxicology, 2021.PMID 33442836
  8. [8]Hilt RJ Editorial: Best Practices in Child Antipsychotic Use Monitoring Journal of the American Academy of Child and Adolescent Psychiatry, 2021.PMID 33176169
  9. [9]Scott JP, Stuth EA, Stucke AG, et al. Droperidol transiently prolongs the QT interval in children undergoing single ventricle palliation Pediatric Cardiology, 2015.PMID 25087057
  10. [10]Minghetti S, Vannini M, Casula L, et al. Epidemiological and Psychopharmacological Study About Off-Label Treatment in Child and Adolescent Psychiatric Emergencies: A Tertiary/Single Center Experience Pediatric Emergency Care, 2022.PMID 35686968
  11. [11]Menard ML, Thümmler S, Giannitelli M, et al. Incidence of adverse events in antipsychotic-naive children and adolescents treated with antipsychotic drugs: Results of a multicenter naturalistic study (ETAPE) European Neuropsychopharmacology, 2019.PMID 31699516
  12. [12]Menard ML, Auby P, Cruzel C, et al. Emergence of psychiatric adverse events during antipsychotic treatment in AP-naive children and adolescents Child and Adolescent Psychiatry and Mental Health, 2022.PMID 36371250

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