Paeds SAQs · preventive-and-community-paediatrics
Vaccine contraindications, precautions and adverse events — formative SAQs
Two formative short-answer questions on true versus false contraindications, live-vaccine rules, anaphylaxis response and AEFI planning.
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SAQ 1 — Screen and decide (10 marks)
A 2-month-old is due for primary immunisations. Mother reports a mild cold, temperature 37.7°C, and says an older cousin “reacted badly” to vaccines and later received an autism diagnosis. The infant is feeding well and looks well. [1] [4]
Questions
- Define contraindication, precaution and false contraindication, and classify each of the mother’s concerns. (4 marks) [1]
- List the essential pre-vaccination safety screen items you still complete. (3 marks) [1] [3]
- State your decision for today and the counselling points you document. (3 marks) [1] [4]
Model answer
Definitions and classification (4). Contraindication: condition that markedly increases serious adverse-reaction risk — withhold that vaccine. Precaution: condition that may increase risk, impair response or confuse later assessment — usually defer. False contraindication: believed barrier without safety justification — vaccinate. Mild cold/low-grade fever in a well infant is a false contraindication (or at most not a reason to cancel). Family autism history is a false contraindication. No true contraindication is described. [1] [4]
Safety screen (3). Identity and vaccines due; prior anaphylaxis to dose/component; severe immunocompromise or suspected IEI before live products; pregnancy only if relevant; recent antibody products before live vaccines; current illness severity; observation/adrenaline readiness. [1] [3]
Decision and counselling (3). Vaccinate today if the screen is clear. Explain expected common reactions, when to seek urgent care, and that autism family history is not a vaccine safety stop. Document consent discussion and rebooking if any temporary issue appears. [1] [4]
References8ShowHide
- [1]Kroger AT General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep, 2006.PMID 17136024
- [2]McNeil MM Risk of anaphylaxis after vaccination in children and adults. J Allergy Clin Immunol, 2016.PMID 26452420
- [3]Shearer WT, Fleisher TA, Buckley RH, et al. Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts. J Allergy Clin Immunol, 2014.PMID 24582311
- [4]Hviid A Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med, 2019.PMID 30831578
- [5]Haber P Postlicensure monitoring of intussusception after RotaTeq vaccination in the United States, February 1, 2006, to September 25, 2007. Pediatrics, 2008.PMID 18519491
- [6]France EK Risk of immune thrombocytopenic purpura after measles-mumps-rubella immunization in children. Pediatrics, 2008.PMID 18310189
- [7]Varricchio F Understanding vaccine safety information from the Vaccine Adverse Event Reporting System. Pediatr Infect Dis J, 2004.PMID 15071280
- [8]Pariyaprasert W Successful treatment of disseminated BCG infection in a SCID patient with granulocyte colony stimulating factor. Asian Pac J Allergy Immunol, 2008.PMID 18595532