Paeds SAQs · clinical-assessment-and-reasoning
Pallor in children: diagnostic approach — formative SAQs
Formative SAQs on paediatric pallor diagnostic approach.
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SAQ 1 (10)
An 18-month-old has progressive pallor, drinks large volumes of cow’s milk, and is otherwise interactive. CBC shows microcytic hypochromic anaemia with low ferritin. [1]
- State a one-sentence problem representation. (2) [1] [6]
- Explain how MCV and reticulocyte count organise the broader anaemia differential beyond this case. (4) [6]
- Outline cause-directed management and how you will prove response. (4) [1]
Model answer
Problem representation. Toddler with dietary risk and confirmed iron-deficiency anaemia without clinical red flags for marrow failure. [1]
Classification grid. MCV sorts micro/normo/macrocytic patterns. Reticulocytes ask whether the marrow is responding: high suggests loss/haemolysis; inappropriately low with severe anaemia suggests production failure. Film refines morphology (hypochromia, spherocytes, blasts). [6]
Management. Reduce excessive cow’s milk, improve dietary iron, start iron per local product guidance, safety-net, and recheck for expected laboratory response; failure to rise triggers rethink of diagnosis, loss or adherence. [1]
References6ShowHide
- [1]Wang M Iron Deficiency and Other Types of Anemia in Infants and Children. American family physician, 2016.PMID 26926814
- [2]Baird DC Alpha- and Beta-thalassemia: Rapid Evidence Review. American family physician, 2022.PMID 35289581
- [3]Shimano KA Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. American journal of hematology, 2021.PMID 34342889
- [4]Gammal RS Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype. Clinical pharmacology and therapeutics, 2023.PMID 36049896
- [5]Carson JL Transfusion thresholds and other strategies for guiding red blood cell transfusion. The Cochrane database of systematic reviews, 2025.PMID 41114449
- [6]Celkan TT What does a hemogram say to us? Turkish archives of pediatrics, 2020.PMID 32684755