Paeds SAQs · ophthalmology
Ophthalmia neonatorum — formative SAQs
Two formative SAQs on ophthalmia neonatorum: a three-day-old with profuse purulent discharge and lid oedema testing the recognition and emergency systemic management of gonococcal ophthalmia, the ceftriaxone-versus-cefotaxime decision and maternal screening; and a ten-day-old with mucopurulent discharge and a staccato cough testing chlamydial ophthalmia with evolving pneumonia, the rationale for systemic erythromycin and the public-health response.
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SAQ 1 — The three-day-old with a profuse purulent eye (10 marks, 15 minutes)
A three-day-old term boy is referred from the postnatal ward with a 12-hour history of profuse, thick, yellow-green discharge from the right eye that reaccumulates within minutes of cleaning. Both eyelids are swollen and chemotic and the eye is intensely red. He was born by spontaneous vaginal delivery after an unbooked pregnancy with no documented antenatal sexually-transmitted-infection screening. [12]
a) What is the most likely diagnosis, and which feature makes it a sight-threatening emergency? State the onset window that supports it. (2 marks) [1]
b) Outline your immediate emergency management, including the specific drug, dose, route and the bedside measure that protects the cornea, before any culture result. (3 marks) [1]
c) The infant is clinically jaundiced. How does this change your drug choice, and why? Name the alternative agent. (2 marks) [1]
d) List the conjunctival swab investigations you would send, and explain why you would not delay treatment while awaiting them. (3 marks) [4] [11]
References8ShowHide
- [1]Castro Ochoa KJ; Gurnani B Ophthalmia Neonatorum (Neonatal Conjunctivitis). StatPearls, 2026.PMID 31855399
- [3]Moore DL; MacDonald NE; Canadian Paediatric Society Preventing ophthalmia neonatorum. Paediatr Child Health, 2015.PMID 25838784
- [4]Curry SJ; Krist AH; Owens DK; et al Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA, 2019.PMID 30694327
- [5]Zikic A; Schunemann H; Wi T; et al Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. J Pediatric Infect Dis Soc, 2018.PMID 30007329
- [6]Zar HJ Neonatal chlamydial infections: prevention and treatment. Paediatr Drugs, 2005.PMID 15871630
- [7]Pinninti SG; Kimberlin DW Neonatal herpes simplex virus infections. Semin Perinatol, 2018.PMID 29544668
- [11]Belagal P Current alternative therapies for treating drug-resistant Neisseria gonorrhoeae causing ophthalmia neonatorum. Future Microbiol, 2024.PMID 38512111
- [12]Tan AK Ophthalmia Neonatorum. N Engl J Med, 2019.PMID 30625059