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Paeds SAQscardiology

Paeds SAQs · cardiology

Myocarditis and pericarditis — formative SAQs

Two formative SAQs on acquired inflammatory heart disease in children: the school-age child who presents a week after a viral illness with chest pain, a raised troponin and ventricular dysfunction, testing the diagnostic triad, the fulminant-myocarditis escalation rule and the selective-immunotherapy principle; and the adolescent with recurrent pericarditis and a friction rub, testing the non-steroidal-anti-inflammatory plus colchicine regimen, the corticosteroid-avoidance principle and the emergency-management of tamponade.

20 marks30 min2 min readVerification in progress

Target exams

RACP General PaediatricsRACP DWEMRCPCH TheoryABP General Pediatrics
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Target exams

RACP General PaediatricsRACP DWEMRCPCH TheoryABP General Pediatrics
Prompt
Myocarditis and pericarditis

SAQ 1 — Acute chest pain with a raised troponin (10 marks, 15 minutes)

A nine-year-old boy presents to the emergency department one week after a febrile respiratory illness with central chest pain, breathlessness on walking and palpitations. He is tachycardic at 130 beats per minute with a gallop rhythm, a respiratory rate of 40, cool peripheries and a capillary refill of four seconds. The high-sensitivity troponin is markedly raised. The electrocardiogram shows widespread ST-segment and T-wave changes with occasional ventricular ectopic beats. The echocardiogram shows a moderately impaired left ventricular ejection fraction with global hypokinesis and a trivial pericardial effusion. A diagnosis of acute myocarditis is made. [1]

a) Outline your diagnostic reasoning, naming the three bedside investigations that anchor the diagnosis and the role of cardiac magnetic resonance. (3 marks) [3]

b) Describe your immediate and stepwise management, including where this child should be managed, the activity-restriction advice and the role (if any) of intravenous immunoglobulin and corticosteroids. (5 marks) [1] [6]

c) Twenty-four hours later the child becomes hypotensive, oliguric and cold, with a rising lactate and sustained ventricular tachycardia. What has happened, and what is the definitive intervention that reverses the course? (2 marks) [8]


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References15ShowHide
  1. [1]Law YM; Lal AK; Chen S; et al Diagnosis and Management of Myocarditis in Children: A Scientific Statement From the American Heart Association Circulation, 2021.PMID 34229446
  2. [2]Tunuguntla H; Jeewa A; Denfield SW Acute Myocarditis and Pericarditis in Children Pediatr Rev, 2019.PMID 30600275
  3. [3]Ammirati E; Moslehi JJ; et al Diagnosis and Treatment of Acute Myocarditis: A Review JAMA, 2023.PMID 37014337
  4. [4]Ferreira VM; Schulz-Menger J; Holmvang G; et al Cardiovascular Magnetic Resonance in Nonischemic Myocardial Inflammation: Expert Recommendations J Am Coll Cardiol, 2018.PMID 30545455
  5. [5]Friedrich MG; Sechtem U; Schulz-Menger J; et al Cardiovascular magnetic resonance in myocarditis: A JACC White Paper J Am Coll Cardiol, 2009.PMID 19389557
  6. [6]Robinson J; Hartling L; Crumley E; et al Intravenous immunoglobulin for presumed viral myocarditis in children and adults Cochrane Database Syst Rev, 2020.PMID 32835416
  7. [7]Li Y; Yu Y; Dong R; et al Corticosteroids and Intravenous Immunoglobulin in Pediatric Myocarditis: A Meta-Analysis Front Pediatr, 2019.PMID 31475124
  8. [8]Kwon HW When should mechanical circulatory support be considered in pediatric patients with acute fulminant myocarditis? Clin Exp Pediatr, 2021.PMID 32972050
  9. [9]McMurray JC; May JW; Cunningham A; et al Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis-A Critical Review of Its Pathogenesis and Treatment Front Pediatr, 2020.PMID 33425823
  10. [10]Wu EY; Campbell MJ; et al Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19 Curr Cardiol Rep, 2021.PMID 34599465
  11. [11]Bozkurt B; Kamat I; Hotez PJ Myocarditis With COVID-19 mRNA Vaccines Circulation, 2021.PMID 34281357
  12. [12]Shahid R; Jin J; Cooper JN; et al Pediatric Pericarditis: Update Curr Cardiol Rep, 2023.PMID 36749541
  13. [13]Imazio M; Gaita F; LeWinter M Evaluation and Treatment of Pericarditis: A Systematic Review JAMA, 2015.PMID 26461998
  14. [14]Alsabri M; Elsayed SM; Alsahlly A; et al Efficacy and Safety of Colchicine in Pediatric Pericarditis: A Systematic Review and Future Directions Pediatr Cardiol, 2025.PMID 39080042
  15. [15]Pérez-Casares A, Cesar S, Brunet-Garcia L, et al. Echocardiographic Evaluation of Pericardial Effusion and Cardiac Tamponade Front Pediatr, 2017.PMID 28484689
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