Paeds SAQs · clinical-assessment-and-reasoning
Fatigue and lethargy in children and adolescents — formative SAQs
Formative SAQs on paediatric fatigue and lethargy diagnostic approach.
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Target exams
SAQ 1 (10)
A 4-month-old is brought to ED. Parents say the baby is "very tired" and has fed poorly for 12 hours. Temperature is 38.6°C. The infant has reduced eye contact and a weak cry. [4]
- Distinguish fatigue from lethargy in this age group and state your immediate priority. (3) [4]
- List five must-not-miss causes of infant lethargy. (3) [1]
- Outline your first 10 minutes of assessment and management principles (no invented drug doses). (4) [4] [6]
Model answer
Fatigue vs lethargy. Fatigue implies reduced energy with preserved interaction. This infant has reduced interaction — lethargy emergency language. Immediate priority is ABCDE threat assessment, not a chronic-fatigue interview. [4]
Must-not-miss examples. Sepsis; meningitis/encephalitis; hypoglycaemia; cardiac failure/myocarditis; raised intracranial pressure or trauma/non-accidental injury; severe anaemia; metabolic crisis; intoxication. (Any five high-threat items scored.) [1]
First actions. Open assessment of airway, breathing, circulation, disability with glucose, exposure; senior help; sepsis-capable pathway if infection likely; parallel history; early escalation if local capability exceeded; clear safety-net only after stabilisation and disposition decision. [4] [6]
References6ShowHide
- [1]Clarke RT Clinical presentation of childhood leukaemia: a systematic review and meta-analysis. Archives of disease in childhood, 2016.PMID 27647842
- [2]Royston AP Severe myalgic encephalomyelitis/chronic fatigue syndrome in children and young people: a British Paediatric Surveillance Unit study. Archives of disease in childhood, 2023.PMID 36456114
- [3]Powers JM Prevention, Screening, Diagnosis, and Treatment of Iron Deficiency and Iron Deficiency Anemia in Infants, Children, and Adolescents: Clinical Report. Pediatrics, 2026.PMID 42324084
- [4]Mills E Association between caregiver concern for clinical deterioration and critical illness in children presenting to hospital: a prospective cohort study. The Lancet. Child & adolescent health, 2025.PMID 40451224
- [5]Marcus CL Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics, 2012.PMID 22926173
- [6]Burvenich R Effectiveness of safety-netting approaches for acutely ill children: a network meta-analysis. The British journal of general practice, 2025.PMID 39117428