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Paeds Casesclinical-pharmacology-and-therapeutics

Paeds Cases · clinical-pharmacology-and-therapeutics

Resuscitate a cyanotic neonate with prostaglandin E1 — OSCE

OSCE clinical-decision and communication station: recognising a duct-dependent neonate, starting prostaglandin E1 at the weight-based dose, anticipating the adverse effects of apnoea, fever and hypotension, defending the target saturation, and explaining the plan to the nurse and family in plain language.

osce clinical decision and communication3 min readVerification in progress

Target exams

MRCPCH ClinicalRACP DCERCPSC Pediatrics
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Study tools

Target exams

MRCPCH ClinicalRACP DCERCPSC Pediatrics
Prompt
A two-day-old term neonate on the postnatal ward has become centrally cyanotic with tachypnoea and poor perfusion. The pulse oximetry is 65 per cent in room air and does not rise with oxygen. The midwife calls you because a duct-dependent congenital heart lesion is suspected and echocardiography is at least an hour away. You have eight minutes to recognise the emergency, start the correct drug at the weight-based dose, anticipate the adverse effects, set the target saturation, and explain the plan to the nurse and to the family.

Candidate brief

You have eight minutes to manage a ward call about a cyanotic two-day-old with a suspected duct-dependent congenital heart lesion. Use a structured approach: recognise the emergency and do not wait for echocardiography, start prostaglandin E1 at the weight-based dose, anticipate and prepare for the adverse effects, set the target saturation, and explain the plan to the nurse and to the family in plain language. [10]

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References3ShowHide
  1. [4]Hsu DT, Pearson GD Heart failure in children: part II: diagnosis, treatment, and future directions. Circ Heart Fail, 2009.PMID 19808380
  2. [7]Batra AS, Silka MJ, Borquez A, et al. Pharmacological Management of Cardiac Arrhythmias in the Fetal and Neonatal Periods: A Scientific Statement From the American Heart Association. Circulation, 2024.PMID 38314551
  3. [10]Taksande A, Jameel PZ Critical Congenital Heart Disease in Neonates: A Review Article. Curr Pediatr Rev, 2021.PMID 33605861
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