Paeds Cases · clinical-pharmacology-and-therapeutics
Resuscitate a cyanotic neonate with prostaglandin E1 — OSCE
OSCE clinical-decision and communication station: recognising a duct-dependent neonate, starting prostaglandin E1 at the weight-based dose, anticipating the adverse effects of apnoea, fever and hypotension, defending the target saturation, and explaining the plan to the nurse and family in plain language.
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You have eight minutes to manage a ward call about a cyanotic two-day-old with a suspected duct-dependent congenital heart lesion. Use a structured approach: recognise the emergency and do not wait for echocardiography, start prostaglandin E1 at the weight-based dose, anticipate and prepare for the adverse effects, set the target saturation, and explain the plan to the nurse and to the family in plain language. [10]
References3ShowHide
- [4]Hsu DT, Pearson GD Heart failure in children: part II: diagnosis, treatment, and future directions. Circ Heart Fail, 2009.PMID 19808380
- [7]Batra AS, Silka MJ, Borquez A, et al. Pharmacological Management of Cardiac Arrhythmias in the Fetal and Neonatal Periods: A Scientific Statement From the American Heart Association. Circulation, 2024.PMID 38314551
- [10]Taksande A, Jameel PZ Critical Congenital Heart Disease in Neonates: A Review Article. Curr Pediatr Rev, 2021.PMID 33605861