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O&G TopicsUrogynaecology — pelvic floor disorders

O&G · Urogynaecology — pelvic floor disorders

Prolapse surgery: native-tissue repair, vaginal apical suspension, sacrocolpopexy and the mesh controversy

Also known as Sacrocolpopexy · Sacrospinous fixation · Uterosacral ligament suspension · Colporrhaphy · Vault prolapse repair · Native tissue repair · Prolapse reconstructive surgery

Exam-exhaustive FRANZCOG fellowship reference on prolapse surgery: native-tissue anterior and posterior colporrhaphy (Altman 2011, Christmann-Schmid 2026), vaginal apical suspension — sacrospinous fixation and uterosacral ligament suspension (OPTIMAL: Barber 2014, Jelovsek 2018), laparoscopic sacrocolpopexy as the gold-standard apical repair (Maher 2004, Nygaard 2004, Maher 2023 RR 2.31), post-hysterectomy vault prolapse, the native-tissue versus mesh evidence (PROSPECT, Yeung 2024), the transvaginal mesh withdrawal (TGA 2018, FDA 2019, Cumberlege 2020), the IUGA/ICS mesh-complication classification, the OPUS anti-incontinence trade-off, and the regional guideline deltas. ANZ primary, globally tagged to MRCOG, ABOG, FRCSC.

high19 referencesUpdated 1 Aug 202612 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Anterior or posterior repair without restoring apical support — recurrence is the predictable consequence
  • Ureteric injury at uterosacral ligament suspension — always confirm ureteric patency with intra-operative cystoscopy
  • Presacral venous bleeding at sacrocolpopexy — a recognised and potentially catastrophic operative risk
  • Transvaginal mesh for primary prolapse (withdrawn ARTG 2018) offered without the full mesh consent conversation
  • Operating without screening for occult stress incontinence — the woman returns cured of the lump but now leaking
  • Mesh exposure or erosion presenting as post-operative discharge or pain dismissed as trivial
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Related topics

  • Pelvic organ prolapse
  • Stress urinary incontinence & midurethral slings
  • Urodynamics
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Anterior or posterior repair without restoring apical support — recurrence is the predictable consequence
  • Ureteric injury at uterosacral ligament suspension — always confirm ureteric patency with intra-operative cystoscopy
  • Presacral venous bleeding at sacrocolpopexy — a recognised and potentially catastrophic operative risk
  • Transvaginal mesh for primary prolapse (withdrawn ARTG 2018) offered without the full mesh consent conversation
  • Operating without screening for occult stress incontinence — the woman returns cured of the lump but now leaking
  • Mesh exposure or erosion presenting as post-operative discharge or pain dismissed as trivial
One-line fellowship answer

Prolapse surgery rebuilds failed vaginal support for symptomatic Stage II to IV prolapse: restore the apex first (laparoscopic sacrocolpopexy is the gold-standard apical repair; uterosacral suspension and sacrospinous fixation are the vaginal alternatives), then repair the anterior and posterior compartments with native tissue, because transvaginal mesh for primary prolapse adds morbidity without symptomatic benefit and was withdrawn (ARTG 2018, FDA 2019, Cumberlege 2020) — and always screen for occult stress incontinence and check ureteric patency.[4][5]

She is 64, post-hysterectomy, and the vault is at the introitus. In theatre you have a choice to defend: a vaginal apical suspension that avoids mesh and recovers quickly, or a laparoscopic sacrocolpopexy that gives the most durable apical support but uses mesh. The examiner wants to hear how you choose — by compartment, by route, by material, by the trials — and how you counsel on recurrence, ureteric injury, mesh exposure and the chance of needing another operation. This topic is that defence.[4][8]

Overview and definition

Prolapse surgery is the reconstruction or closure of failed vaginal support for symptomatic pelvic organ prolapse that has not responded to, or is unsuited to, conservative management.[1] It is classified in two orthogonal ways — by route and by material — and the candidate who names both sounds like a consultant.

  • By route: abdominal (open, laparoscopic or robotic), vaginal reconstructive, or vaginal obliterative (colpocleisis).[4]
  • By material: native tissue (fascial plication), abdominally placed synthetic mesh (sacrocolpopexy), biological graft, or transvaginal mesh kits (withdrawn for primary prolapse).[15]

Two numbers anchor the topic: the lifetime surgical risk of 11.1% by age 80, and a reoperation rate of 29.2% with the interval shortening each round.[3]

Headline surgical numbers examiners expect

RR 2.31Sacrocolpopexy vs vaginal: awareness of prolapseMaher 2023 — vaginal procedures worse (95% CI 1.27 to 4.21)
61.5% vs 70.3%OPTIMAL: 5-year surgical failureULS vs SSLF, not significantly different (Jelovsek 2018)
60.8% vs 34.5%Anterior mesh vs native: 1-year anatomyAltman 2011 NEJM — anatomy, not symptoms
~11.8%Transvaginal mesh exposureYeung 2024; surgery for exposure 6.1%
[3] [4] [6] [7] [15]
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References19ShowHide
  1. [1]Bump RC, Mattiasson A, Bø K, Brubaker LP, DeLancey JO, Klarskov P, Shull BL, Smith AR The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction Am J Obstet Gynecol, 1996.PMID 8694033
  2. [2]DeLancey JO Anatomic aspects of vaginal eversion after hysterectomy Am J Obstet Gynecol, 1992.PMID 1615980
  3. [3]Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence Obstet Gynecol, 1997.PMID 9083302
  4. [4]Maher C, Yeung E, Haya N, Christmann-Schmid C, Mowat A, Chen Z, Baessler K Surgery for women with apical vaginal prolapse Cochrane Database Syst Rev, 2023.PMID 37493538
  5. [5]Barber MD, Brubaker L, Burgio KL, et al. Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: the OPTIMAL randomized trial JAMA, 2014.PMID 24618964
  6. [6]Jelovsek JE, Barber MD, Brubaker L, et al. Effect of Uterosacral Ligament Suspension vs Sacrospinous Ligament Fixation With or Without Perioperative Behavioral Therapy for Pelvic Organ Vaginal Prolapse on Surgical Outcomes and Prolapse Symptoms at 5 Years in the OPTIMAL Randomized Clinical Trial JAMA, 2018.PMID 29677302
  7. [7]Altman D, Väyrynen T, Engh ME, Axelsen S, Falconer C; Nordic Transvaginal Mesh Group Anterior colporrhaphy versus transvaginal mesh for pelvic-organ prolapse N Engl J Med, 2011.PMID 21561348
  8. [8]Nygaard IE, McCreery R, Brubaker L, et al. Abdominal sacrocolpopexy: a comprehensive review Obstet Gynecol, 2004.PMID 15458906
  9. [9]Maher CF, Qatawneh AM, Dwyer PL, Carey MP, Cornish A, Schluter PJ Abdominal sacral colpopexy or vaginal sacrospinous colpopexy for vaginal vault prolapse: a prospective randomized study Am J Obstet Gynecol, 2004.PMID 14749629
  10. [10]Schimpf MO, Abed H, Sanses T, et al. Graft and Mesh Use in Transvaginal Prolapse Repair: A Systematic Review Obstet Gynecol, 2016.PMID 27275813
  11. [11]Siddiqui NY, Grimes CL, Casiano ER, et al. Mesh sacrocolpopexy compared with native tissue vaginal repair: a systematic review and meta-analysis Obstet Gynecol, 2015.PMID 25560102
  12. [12]Glazener C, Breeman S, Elders A, et al. Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study - results from the PROSPECT Study Health Technol Assess, 2016.PMID 28052810
  13. [13]Reid FM, Elders A, Breeman S, et al. How common are complications following polypropylene mesh, biological xenograft and native tissue surgery for pelvic organ prolapse? A secondary analysis from the PROSPECT trial BJOG, 2021.PMID 34473896
  14. [14]Christmann-Schmid C, Baessler K, Yeung E, et al. Surgery for women with anterior compartment prolapse Cochrane Database Syst Rev, 2026.PMID 42029168
  15. [15]Yeung E, Baessler K, Christmann-Schmid C, Haya N, Chen Z, Wallace SA, Mowat A, Maher C Transvaginal mesh or grafts or native tissue repair for vaginal prolapse Cochrane Database Syst Rev, 2024.PMID 38477494
  16. [16]Haylen BT, Freeman RM, Swift SE, et al. An International Urogynecological Association (IUGA) / International Continence Society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) & grafts in female pelvic floor surgery Int Urogynecol J, 2011.PMID 21140130
  17. [17]Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, Amundsen CL, Schaffer J, Meikle SF, Spino C A midurethral sling to reduce incontinence after vaginal prolapse repair N Engl J Med, 2012.PMID 22716974
  18. [18]Winkelman WD, Modest AM, Richardson ML U.S. Food and Drug Administration Statements About Transvaginal Mesh and Changes in Apical Prolapse Surgery Obstet Gynecol, 2019.PMID 31503162
  19. [19]Unger CA, Walters MD, Ridgeway B, Jelovsek JE, Barber MD, Paraiso MF Incidence of adverse events after uterosacral colpopexy for uterovaginal and posthysterectomy vault prolapse Am J Obstet Gynecol, 2015.PMID 25434838

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PreviousPelvic organ prolapseUrogynaecology — pelvic floor disordersNextStress urinary incontinence & midurethral slingsUrogynaecology — pelvic floor disorders

Related topics

  • Pelvic organ prolapse
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  • Urodynamics